Clinical Benefits of Metabolic Therapy of Ischemic Heart Disease with L-Arginine Supplementation
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2016, Vol 2, Issue 9
Abstract
Abstract: Ischemic heart disease (IHD) - one of the major human diseases, which account for a significant portion of all cardiovascular deaths of the world. In spite of recent decrease in cardiovascular mortality, IHD remains the leading cause of death in the developed world. The application of surgical and percutaneous myocardial revascularization promised to be a safe and effective method to control symptoms and to improve prognosis in this disease. However, clinical results do not match these expectations: most revascularized patients remain symptomatic, a large fraction continues to require antianginal medications, and about 10% suffer of either death or myocardial infarction within 2.5 years.In the meanwhile, the clinical variety of IHD is rapidly changing, with a growing prevailing of elderly patients, diabetics, and heart failure patients. Pharmacologic intervention of cardiac energy metabolism, by enhancing the synthesis of nitric oxide (NO) via administration of L-arginine, appears as an innovative and attractive addition to treatment of IHD patients. Keywords: Angina, cardiac energy metabolism, ischemic heart disease, L-arginine
Authors and Affiliations
A. L. Alyavi, B. A. Alyavi, N. Ya. Sayfiyev, D. K. Tulaganova, D. I. Radjabova, Sh. A. Iskhakov, Sh. I. Azizov, B. B. Toshev
Keywords
Related Articles
- EP ID EP388432
- DOI -
- Views 109
- Downloads 0
A Prospective and Interventional Study of the Role of Low Dose Mifepristone in the Management of Uterine Leiomyoma in Perimenopausal Women
Abstract:The objective of this study is to determine the effect of progesterone antagonist, Mifepristone in perimenopausal women in decreasing the severity of symptoms like menorrhagia, dysmenorrhea, abdominal pain and u...
Castelli Risk Index, Atherogenic Index of Plasma, and Atherogenic Coefficient: Emerging Risk Predictors of Cardiovascular Disease in HIV-Treated Patients
Abstract:Atherogenic cardiovascularrisk assessment is important in the management of dyslipidaemia associated with antiretroviral therapy (ART). Generally, Castelli’s Risk Index (CRI), Atherogenic Index of Plasma (AIP) a...
Kinetic and Thermodynamic Properties of Immobilized Lettuce Protease and Its Role in Production of Novel Bile Binding and Tyrosinase Inhibitory Peptides from Some Plant Wastes
Abstract:This study was designed to compare the properties, kinetics and stability of the immobilized lettuce protease with the free one. We also aimed to test the use of the immobilized lettuce protease for the producti...
Dengue fever complicated with Non-STEMI
Abstract: Dengue is a vector born viral infection that belongs to family Flaviviridae. It is a single stranded RNA virus and endangers 2.5 billion people world wild. Dengue viral (DENV) infections cause a broad spectrum...
Thyroid Hormones and Lipid Profile Abnormalities
Abstract:This study was aimed to investigate the association between thyroid disorders and lipid profile in 122 patients (100 females and 22 males ) referred to the Specialized Center for Endocrinology and...