Clinical, Biological and Genetic Predictors of Lithium Treatment Response
Journal Title: Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry - Year 2018, Vol 10, Issue 4
Abstract
Lithium was discovered by the Swedish Arfvedson at the beginning of the 1800s and began to be used in psychiatry for the past 1950s. Lithium, as a mood stabilizer, is the gold standard and first choice treatment agent for the treatment of bipolar disorders in adults. However, it is mostly difficult in clinical practice to predict which patient would respond to the treatment with lithium well due to the huge variation in patients’ characteristics. Clinicians seem to focus primarily on identifying a clinical phenotype to foresee lithium treatment response. In this article, researches on predictors of the lithium treatment response were reviewed and evaluated in four titles as clinical, biochemical, neuroimaging and genetic predictors.
Authors and Affiliations
Hazan Tomar Bozkurt, Vefa Erbasan, Ümran Eğilmez, Barış Şen, Memduha Aydın, Kürşat Altınbaş
Symptom Similarities and Differences in Anxiety and Depressive Disorders
The question if there is a valid distinction between depression and anxiety disorders remains controversial. These two disorders have various overlaps in the symptomatology and sometimes it is difficult to make a clear d...
Suicide and Personality
Many factors play role in the emergence of suicidal behavior has been accepted. Familial tendency including some features of personality structure, hopelessness, affective disorder, and suicide behavior attracts attenti...
Psikotik Bozukluklarda Mikrokimerizm Etyolojik Bir Faktör Olabilir mi? Bir Hipotez Önerisi
Bu editöre mektupta, mikrokimerizmin psikotik bozuklukların nedenini açıklayabilecek bir etyolojik faktör olabileceği biçiminde bir hipotez ortaya konmuş ve bu varsayımı değerlendirmede kullanılabilecek bazı çalışma öner...
Depresyon ve İrritabl Barsak Sendromu Birlikteliğinin Nörobiyolojisi
İrritabl barsak sendromu (İBS) yaşamı güçleştiren ve depresyonla birlikteliği çok sık karşılaşılan işlevsel bir barsak hastalığı olmasına karşın altında yatan düzenek tam olarak aydınlatılamamıştır. Tanı ölçütleri...
From Work Life to School: Theoretical Approaches for School Burnout
The concept of burnout, which was dealt within the context of working life in the beginning, has begun to be examined by adapting it to the school environment. Burnout, defined as a decline of energy physically, emotiona...