Clinical Biomarkers and Biotechnology in Fertile Window
Journal Title: Interventions in Gynaecology and Women’s Healthcare - Year 2018, Vol 2, Issue 2
Abstract
The recognition of fertility is increasingly important in prestigious scientific groups and in renowned international schools [1]. In this sense, we have tried to objectify the changes observed in the evolutionary process in the fertile window produced by the effect of estrogen and progesterone. Among the most relevant schools with this methodology are some authors such as; Hilgers[2], Stanfort[3], Scarpa [4], Aldecreutz[5], Ecochard[6] etc. These relevant contributions are based on the same clinical principle of fertile clinical window, which are based on the changes of cervical secretion pattern throughout the menstrual cycle. The fundamentals of this interest are justified in the perspectives that the application of the accumulated research of the basic principles of ovarian physiology pose. The pulsatile release of gonadotropinreleasing hormone (GNRH) stimulates the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the anterior pituitary gland. These two hormones are responsible for stimulating the secretion of estrogen and progesterone at the level of the ovary, which justifies the physicochemical changes that occur in the cervical secretion [7]. Another aspect derived from clinical research in this field is the biotechnological implications derived from the biophysical properties of cervical secretion in the recognition of fertility. In this same line, the number of companies recognized by the scientific community in the development of devices related to the recognition of fertile time has increased. Among them: Swiss Precision Diagnostics (SPD) GmbH (Switzerland), Church & Dwight Co., Inc. (USA), Prestige Brands Holdings, Inc. (USA), Fairhaven Health, LLC (USA) ,HiLin Life of the product, Inc. (USA), Fertility Focus Limited (UK), and Geratherm Medical AG (Germany). According to a report recently published by Markets and Markets, the global market for devices, or so-called fertility tests, during the projected period of 2015 to 2020 is estimated to reach USD 151.0 million. Additionally, investment in this type of technology is forecast to grow at a compound annual rate of 7.5% during the 2015-2020 forecast period to reach USD 216.8 million in 2020 (Figure 1). Since 2015, to mention one of the recently studied intervals in time, the region between the United States and Canada had one of the largest shares in the global market of devices and tests for the recognition of fertility. The expectations in this respect are evident in the results obtained in devices developed to diagnose fertility tests in the mentioned regions, and it is expected that in Asia and the Pacific a greater annual growth will be reached (Figure 2). Another fact that stands out is the interest associated with the greater number of patent applications in devices for the recognition of fertility, with China leading the market, followed by the US office, as observed in the time interval included between 2007-2010 (Figure 3). Among the main applicants are Aronne Louis J with 3.8% of the applications, Kosasky; Harold J., President and Fellows of Harvard College, and The Regents of the University of California each with 1.4% of the applications.
Authors and Affiliations
Murcia Lora José María
Keywords
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- EP ID EP573233
- DOI 10.32474/IGWHC.2018.02.000135
- Views 70
- Downloads 0
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