CLINICAL CASE OF PROGRESSIVE SUPRANUCLEAR PARALYSIS (STEELE-RICHARDSON-OLSHEWSKI SYNDROME)
Journal Title: International scientific journal Science and Innovation - Year 2024, Vol 3, Issue 6
Abstract
Progressive supranuclear palsy is a rare neurodegenerative disease affecting the central nervous system [1], characterized by progressive impairment of voluntary eye movements, bradykinesia, muscle rigidity with simultaneous dystonia of the axial muscles, and dementia [1]. PSP, also known as Steele-Richardson-Olszewski syndrome, affects men and women equally [5]. In the early stages, patients with PSP often have trouble walking, balancing, and falling backward, often many times a day; some find it difficult to walk and feel like their feet are glued to the floor; patients experience difficulty with eye movements, especially downward gaze, as well as difficulty opening the eyes[5]. This disease is an atypical form of Parkinson's disease. In this disease, degeneration of neurons in the basal ganglia and brain stem is observed with the presence of neurofibrillary tangles containing excessively phosphorylated tau protein[1]. Progressive supranuclear palsy with Richardson syndrome (PSP-SR): classic progressive supranuclear palsy with progressive supranuclear ophthalmoplegia and severe balance impairment (most common form, in ≥ 70% of cases) [3]. At the moment, the etiology of this pathology is unknown. Patients with PSP have a poor prognosis, which is associated with early cognitive impairment, dysphagia, and death within 10 years due to aspiration.
Authors and Affiliations
Aripova N. F. , Omonova U. T.
Keywords
Related Articles
- EP ID EP741515
- DOI 10.5281/zenodo.12599829
- Views 14
- Downloads 0
VOICE IDENTIFICATION SYSTEMS
This article provides detailed information on the problems and methods of identification of a person based on biometric parameters, and it is presented that the identification of a person based on his voice is safe and i...
CHANGES IN ALCOHOL BEHAVIOR DURING THE COVID-19 PANDEMIC AND BEYOND
It is clear that during and after the Covid-19 pandemic, alcohol consumption schemes and their consequences will change. While the results of changes in alcohol behavior during lockdown are not consistent, there have bee...
THE IMPORTANCE OF THE SCALE OF THE VIEWING ANGLE IN PERSPECTIVE
Analysis of solutions to the problem of students' ability to choose the right distance and the correct setting of the viewing angle in relation to the field of view
USAGE OF ENGLISH LITERATURE IN EFFECTIVE TEACHING AND LEARNING LANGUAGE IN ESL CLASSES
The paper presents information about literary texts material usage as a tool for creating interesting and effective teaching and learning atmosphere in the ESL classroom, plus the appropriate ways for material selecting...
APPLICATION OF DIGITAL TECHNOLOGIES IN POWER SUPPLY MANAGEMENT AND MONITORING SYSTEMS
This article is devoted to the study of the application of modern digital technologies such as the Internet of Things (IoT), data analytics, artificial intelligence, etc., in energy supply management and monitoring syste...