Clinical efficacy of sustained release chlorhexidine in collagen membrane in the non surgical management of chronic localised periodontitis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Background: Aim of the study is to determine the efficacy of sustained release chlorhexidine in collagen membrane in the management of chronic localised periodontitis Materials and methods: The study was conducted using 2.5 mg of chlorhexidine incorporated in fish collagen membrane. Patients with localized periodontitis with 5-8 mm pocket depth and single rooted teeth with involvement of one or two surfaces were included for the study. After one week of initial therapy (scaling) patients who maintain oral hygiene with PPD 5-8 mm were randomly assigned to control and test group of 61 sites each (35 patients in test group and 23 patients in control group). Test groups received Scaling and Root planing (SRP )+ collagen chlorhexidine chip while the control group received SRP alone. Parameters probing pocket depth (PPD), clinical attachment level (CAL) and gingival index (GI) were recorded at baseline and at 1 ,3, 6 and 9 months were compared. Results: The test groups showed a significant reduction in PPD and gain in CAL (P-value < 0.0001) 5.89 ± 0.97 at baseline to 3.30 ± 1.16 at 9 months when compared to controls (5.51±0.92 , 4.86±1.50 )and reduction in gingival index (2.00 ± 0.00 at baseline to 0.33±0.47 at 9 months) when compared to control sites (1.96± 0.20 at baseline to 1.20± 0.60 at 9 months) which is statistically significant. Conclusion: Local drug delivery using collagen chlorhexidine chip along with SRP is a predictable treatment option for the non surgical management of chronic localized periodontitis.The need for detailed microbiological study persist to corelate with the clinical findings observed.
Authors and Affiliations
Dr. Divya P V— MDS*, Dr Bindu R Nayar – MDS MPhil, Dr. K Nandakumar —MDS ***
Keywords
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- EP ID EP365850
- DOI 10.9790/0853-1702162229
- Views 54
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