Clinical, electrophysiological and pathological evaluation of limb girdle weakness
Journal Title: Asian Pacific Journal of Health Sciences - Year 2016, Vol 3, Issue 4
Abstract
Introduction: Limb girdle weakness is one of the frequent clinical diagnoses in neurological clinics. Their etiology, treatment and prognosis are varied in different geographical regions of the world. Materials and methods: Patient cohort of 68 patients with limb girdle weakness from a tertiary hospital in South India were studied. Results: Most of the patients were found to have muscular dystrophies with LGMD variety being the highest reported. Out of 48 cases of muscle disorders LGMD [17/48] and DMD [14/48] formed the majority. Very few of them had a family history and they had little evidence of cardiac involvement. Males were more affected in DMD and BMD. LGMD males outnumbered female patients in this study. Conclusion: Our study reports that muscular dystrophies claim a major share of limb girdle weakness. It is very important to understand the precise etiology and to identify patients prone to life threatening cardiac, pharyngeal or respiratory muscle involvement.
Authors and Affiliations
Dr A Sridhar
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