Clinical Evaluation of Efficacy of Dexmedetomidine in Maintaining Intraoperative Haemodynamics in Posterior Fixation Surgery Following Traumatic Spine Injury
Journal Title: International Journal of Biomedical and Advance Research - Year 2017, Vol 8, Issue 4
Abstract
Aim and Objectives: The present study was undertaken to compare the efficacy and safety of dexmedetomidine versus nitroglycerin in maintaining intraoperative haemodynamic stability and postoperative recovery profile in adult patients undergoing posterior fixation surgery for traumatic spine injuries. Methods: The study enrolling 60 patients of either sex (age 18-50 years), ASA grade I and II were randomly allocated into two groups of thirty patients each. Group DEX received dexmedetomidine 1?g/kg infusion (diluted in 50 ml of 0.9% normal saline) and group NTG received 50 ml of 0.9% normal saline infusion over a period of 10 min as bolus before premedication. The intraoperative haemodynamic parameters, estimated blood loss, operative time, intra and post operative complications, post operative sedation and recovery in patients were noted and compared between two groups. Results: Dexmedetomidine had better intraoperative haemodynamic stability than nitroglycerine, (p<0.05). The mean blood loss and duration of surgery was less with dexmedetomidine than with nitroglycerin, (p<0.01). Dexmedetomidine has fewer episodes of complications viz; tachycardia, bradycardia, hypotension and hypertension during and after surgery as compared to nitroglycerin. Post operative sedation was more with dexmedetomidine as compared to nitroglycerin, (p<0.05). Conclusion: Dexmedetomidine is an effective and safe agent in maintaining intraoperative hemodynamics in adults undergoing posterior fixation spine surgery.
Authors and Affiliations
Lulu Fatema Vali, Rajeshkumar G. Dwivedi, Abdul Hussain Vali
Keywords
Related Articles
- EP ID EP383798
- DOI 10.7439/ijbar.v8i4.4102
- Views 80
- Downloads 0
Pilot Study on the Stability of Internal Quality Control Samples For Anti-HCV Immunodiagnostic Assays
Laboratory diagnosis of HCV infection is usually made on the basis of the detection of circulating antibodies. All laboratories carrying out anti-HCV tests, should have a well-functioning quality assurance programme. Qua...
Behaviour Pattern regarding HIV/AIDS among Students of Selected Professional Institutes of Ghaziabad District of Uttar Pradesh.
Introduction: The annual number of AIDS-related deaths globally has been decreasing due to the significant scaling up of ART over the past few years. The estimated number of people who died from HIV- related illness in 2...
Study of short course prophylactic antibiotic treatment (24hrs) in clean surgeries
Surgical site infections are the third most common type of nosocomial infections(over 70%). In any hospital, perioperative antimicrobial prophylaxis constitutes the bulk of antimicrobial consumption. We need to adapt pol...
Histopathology of soft tissue tumors in association with immunohistochemistry
Aim: To study the histopathological pattern for understanding the classification and type of soft tissue tumors. To find out the relative incidence of benign and malignant soft tissue tumors and to classify the soft tiss...
Effectiveness of mulligans taping for the short term management of plantar heel pain Randomised control trial
Introduction: Plantar fasciitis is one of the most common causes of plantar heel pain. Numerous nonsurgical interventions such as rest exercise & modalities focus on relieving the symptoms associated with plantar heel pa...