Clinical evaluation of epidural bupivacaine, butorphanol, and butorphanol - bupivacaine combination in goat
Journal Title: UNKNOWN - Year 2019, Vol 26, Issue 1
Abstract
Butorphanol is a synthetic opioid commonly used for epidural anesthesia in human either alone or in combination with bupivacaine but not in goat. The objective of the present study was to evaluate the analgesic effect of epidural butorphanol either alone or in combination with bupivacaine. Fifteen adult apparently healthy goats were randomized into three equal groups to receive a lumbosacral epidural injection of bupivacaine 0.5 % (0.5 mg/kg), butorphanol 1% (0.08 mg/kg) or their combination (bupivacaine 0.25 mg/kg and butorphanol 0.04 mg/kg). Animals were observed for incoordination of hind limbs, perineal pin prick and sedation at 10 minutes interval. Heart rate, respiratory rate and rectal temperature were assessed every 15 minutes. Epidural butorphanol resulted into significantly (P < 0.05) rapid analgesia (9.8 ± 1.1 Min) than the butorphanol– bupivacaine combination (12.8 ± 0.84 Min) and bupivacaine (16.6 ± 0.55). Butorphanol-bupivacaine combination provoked significant ((P < 0.05) prolonged intense analgesia (208 ± 8.36 Min) compared to either bupivacaine (112 ± 8.37) or butorphanol (166 ± 5.48 Min). Ataxia accompanied administration of bupivacaine either alone or in combination with butorphanol, while sedation was observed in animals received butorphanol alone or combined with bupivacaine. No significant changes were observed in heart rate, respiratory rate or rectal temperature. The epidural administration of butorphanol-bupivacaine combination promoted longer-lasting analgesia in goats without motor disturbances compared to bupivacaine alone. This combination might prove useful clinically to provide analgesia in goats for long-duration perineal obstetrical or surgical procedures.
Authors and Affiliations
Hagag U. 1*, Mahmoud M. M. 2 1 Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef 62511, Egypt. 2 Department of Animal Medicine (Veterinary Internal Medicine), Faculty of Veterinary Medicine, BeniSuef University, Beni-Suef 62511, Egypt.
Keywords
Related Articles
- EP ID EP104388
- DOI 10.21608/jvmr.2019.43338
- Views 172
- Downloads 0
The ameliorative effect of methanolic red carrot extract and vitamin E against cadmium-induced testicular toxicity in rats
The current study aimed to investigate the effects of methanolic red carrot extract (MRCE) against cadmium intoxication on testis of adult Wister albino male rats. For that purpose, forty eight Wister albino male rats...
A study on the effect of age, breed and season on sexual behaviour, testosterone concentrations and scrotal circumference in Egyptian rams
The objective of this study was to detect the influence of age, breed and season on sexual behaviour, testosterone concentrations and scrotal circumference in Egyptian rams. The study was carried out at agricultural r...
Microbiological evaluation of chicken meat products
The aim of the present study was to compare the microbiological quality and safety of chicken products collected from a poultry processing plant and from the retail market. The collected samples represented 120 chicken p...
Fungal pathogens associated with respiratory problems in broiler chickens
Fungal diseases of poultry have become problematic as bacterial and viral diseases. Therefore, this study was designed to investigate the prevalence of fungal agents in broiler chickens suffering from respiratory disor...
The incidence of C. perfringens in chickens in different seasons and Governorates in Egypt
A total of 247 intestinal samples from freshly dead broiler and layer chickens were collected from 150 farms in Giza, Sharkia, Qalubia, El-Behera, Daqahlia and Cairo governorates in different seasons. These samples sho...