Clinical Evaluation of the Tonsils for Malignancy: The Necessity of Histopathological Examination
Journal Title: Medical Laboratory Journal - Year 2018, Vol 12, Issue 1
Abstract
Background and Objectives: Tonsils are lymphoid tissues that can be affected in various diseases. In some cases, it is necessary to remove tonsils through surgery. Although the diseases are often diagnosed by history-taking and physical examination that proceeds with surgery, histologic examination is necessary for confirmed diagnosis of malignancy. Considering the low prevalence of tonsil cancer, this study was performed to clinically examine tonsils for malignancies and evaluate the necessity of histopathological examination. Methods: This retrospective study was conducted on 2,232 patients (aged 2-80 years) who had undergone tonsillectomy for various reasons in the city of Gorgan from 2001 to 2012. Medical history was obtained and physical examination was carried out before surgery. All the obtained samples were sent to the laboratory for histopathological examination. Finally, the collected data was analyzed. Results: Only one case of lymphoma was found among the 2,232 patients investigated in this study. This 80-year-old woman with preoperative cervical lymphadenopathy and unilateral tonsillar enlargement went under tonsillectomy for confirmed diagnosis. Conclusion: Considering the high frequency of tonsillectomy and the low possibility of malignancy, and the fact that malignancy is often seen in individuals with obvious clinical presentations such as in our case, it is recommended to limit referral of specimens for histological examination to highly suspicious cases through more rational decision-making and summarization of other findings.
Chronic Respiratory Allergy Caused by Lophomonas blattarum: A Case Report
ABSTRACT Background and Objective: Lophomonas blattarum is a multi-flagellate protozoan that is commensal in hindgut of cockroaches and other insects. The protozoan can cause respiratory infection in humans. Most...
Molecular Detection of Hepatitis A Virus in Urban Sewage in Isfahan, Iran
ABSTRACT Background and Objectives: Hepatitis A virus (HAV) enters sewage through the stool of infected patients and contaminates freshwater and seawater. The aim of present study was quantitative molecular de...
Survey of Coronaviruses Infection among Patients with Flu-like Symptoms in the Golestan Province, Iran
Background and objectives: Coronaviruses are the main causes of respiratory tract infections in humans. They are also the second leading cause of common cold after rhinoviruses, and can lead to otitis media and asthma. T...
In Vitro Effect of Methanolic Extract of Quercus infectoria Galls on Promastigotes and Amastigotes of Leishmania major (MRHO/IR/75/ER)
Background and objectives: Leishmania major is a flagellated parasitic protozoan that causes cutaneous leishmaniasis. Pentavalent antimony compounds are considered the first-line drugs in the treatment of cutaneous leish...
Efficacy of Mupirocin Ointment in Eradication of Staphylococcus aureus Nasal Carriage in Intensive Care Unit Staff and Patients
Background and Objectives: Staphylococcus aureus is one of the most common causes of morbidity and mortality among intensive care unit (ICU) patients. Nasal carriage is one of the main routs of S. aureus transmission bet...