Clinical features of 80 cases with adrenal incidentaloma
Journal Title: Ege Tıp Dergisi - Year 2015, Vol 54, Issue 3
Abstract
Aim: The detection rate of adrenal incidentaloma with the increasing use of imaging techniques has increased. In this study, we present the clinical features of our cases with adrenal incidentaloma. Materials and Methods: We investigated the data of the cases with adrenal incidentaloma admitted to Endocrine clinic of Ege University between February 2013 and February 2014. Age, sex, comorbidity, localization, size, function, operation method, histological findings were retrospectively recorded. Results: Out of 80 patients, 55 were female (68.7%) and 25 were male (31.3%). Mean age was 55.7±9.7 (30-72). Adrenal incidentaloma was often found between 50 and 60 years of age. In the localization analysis, 51.3% of adrenal mass was detected on the left side, 38.5% on the right and 10.2% was bilateral. When 76 out of 80 patients undertook a hormonal analysis, 73.7% of the adrenal masses were found to be non-functioning. 19.7% of our patients were diagnosed as subclinical Cushing syndrome (when threshold value was taken as 1.8μg/dL in 1mg dexamethasone suppression test-DST), 5.3% pheochromocytoma and 1.3% Conn syndrome. When threshold value was taken as 5μg/dL in 1mg DST, the rate of subclinical Cushing syndrome decreased to 2.6%. Out of 17 patients underwent adrenalectomy, it was observed in the ones with available medical reports that 10 patients were operated with laparoscopic and 5 with robotic surgery. In the pathological data analysis, there were 9 adenoma, 4 pheochromocytoma, 2 myolipoma and 1 oncocytoma. Conclusion: The features of our cases with adrenal incidentaloma were generally found to be in compliance with the the literature data. However, the number of the patients with subclinical Cushing syndrome after 1mg DST may vary according to threshold values. When threshold value was taken as 1.8 μg/dL in 1mg DST, specificity of the test may decrease.
Authors and Affiliations
Nilüfer Özdemir KUTBAY, Banu ŞARER YÜREKLİ, Esma PEHLİVAN, Özer MAKAY, Mehmet ERDOĞAN, Şevki ÇETİNKALP, Gökhan ÖZGEN, Füsun SAYGILI
Keywords
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- DOI 10.19161/etd.344130
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