Clinical outcomes following enhanced respiratory support in ILD Patients with acute Respiratory failure
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
The outlook for patients with ILD presenting to hospital needing respiratory support is poor be it non-invasive ventilation or mechanical ventilation. Based on the available evidence it is difficult to determine a clear role for NIV in patients with ILD. We undertook a retrospective analysis of patients with ILD admitted with acute respiratory failure requiring enhanced respiratory support. We intended to evaluate the outcome from enhanced respiratory support and to ascertain the variables that portend prognosis. 54 patients with a median age of 75.8 (±1.29) and a diagnosis of ILD needed enhanced respiratory support. 65% were male. Mortality for patients admitted to RHDU was 67%. 7% of patients died within 30 days of discharge, 9% died within 3 months and 11% survived beyond 1 year from admission. Time from diagnosis to presentation with ARF was significantly greater in the deceased group, median duration 18.7 (±3.76) vs. 8.5 (±9.33) months in the survivors (p=0.047). There was no difference in lung function, admission arterial blood gas or biochemistry. 43% of patients had IPF; 83% died during their stay. The mortality for patients with ILD admitted for ARF is high and early decisions for escalation of care is critical in making treatment decisions.
Authors and Affiliations
Andrew Achaiah, Matthew Quint, Olivia Bird, K. Suresh Babu
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