Clinical Outcomes from Surgically Treated Hypopharyngeal and Laryngeal Carcinomas in A Tertiary Care Center
Journal Title: International Journal of Medical and Health Sciences - Year 2016, Vol 5, Issue 3
Abstract
Background: Despite advances in techniques and dose regulation of chemoradiotherapy, surgery still plays great role in treating large fraction of well selected locally advanced laryngeal and hypopharyngeal carcinoma. Materials and methods: A retrospective study of 116 cases of surgically treated laryngeal and hypopharyngeal carcinomas from 2009 to 2011 were analysed. Results :The most common sub site of involvement was supraglottis (39.6%) followed by hypopharnyx (36.2%) , glottis (16.3%) and transglottic malignancy (7.7%) respectively. Total laryngectomy was carried out for 108 patients, 18 0f them required Modified radical neck dissection along with laryngectomy. Near total laryngectomy was done in 8 cases after. Patients stayed in hospital for an average of 14 days (range 11—42) after surgery. Histopathologically squamous cell carcinoma was the most common and 2 patients had spindle cell tumour. 92 patients were referred for adjuvant therapy with RT and of which 68 received both chemotherapy and radiotherapy and 18 defaulted from adjuvant therapy. Recurrences were noted both locoregionally and distant in 14% of cases. The mean follow up period was 16 months ranging from 3 months to 35 months. Conclusion : Surgical modality as definitive treatment in well selected Indian population with locally advanced stage III and IV laryngeal and hypopharyngeal carcinomas, with adjuvant therapy when indicated, is a valuable option with less complications and morbidity achieving acceptable locoregional control. A regular follow up is warranted to detect the early locoregional and distant failures.
Authors and Affiliations
Krishnappa R, Vasanth Kumar Gunasekaran
Keywords
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