Clinical profile and outcome of children admitted for dengue with warning signs and severe dengue
Journal Title: Medpulse International Journal of Pediatrics - Year 2017, Vol 3, Issue 1
Abstract
Objective: To study clinical profile and outcome of children with dengue with warning signs and severe dengue. Design: Prospective observational study over period of one year. Subjects and methods: Ninety five children diagnosed as dengue with one or more warning signs on presentation or with severe dengue features were enrolled .Those suffering from dengue fever but without warning signs were excluded from study. Their clinical features, serial hematological and other investigations were noted. Fluid therapy and other supportive treatment was done according to WHO and IAP infectious disease chapter guidelines. The outcome was assessed in terms of course in hospital. Results: Total 95 children were enrolled, 67 with dengue warning signs and 28 with severe dengue. Common warning signs were abdominal pain/tenderness, liver enlargement, lethargy and restlessness. Those with severe dengue had respiratory insufficiency due to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS), refractory shock and severe bleeding. Two presented with dengue encephalitis. Of 95 children enrolled in study 7 (7.36%) died. Case fatality rate was more (21.4%) in those who presented with severe dengue compared with those who presented with warning signs (1.4%). Conclusion: Dengue is one of the dreaded fevers of pediatric age group. Dengue has variable clinical presentation. But, timely picking up cases with set of warning signs given by WHO in critical phase of illness followed by stepwise protocol based fluid therapy can reduce case fatality.
Authors and Affiliations
N S Shewale
Keywords
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- EP ID EP483564
- DOI 10.26611/1014316
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