Clinical Profile of Haemophilia Patients in Jammu Region
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 11
Abstract
Abstract: Haemophilia is a group of related inherited bleeding disorders that include abnormalities of coagulation factors and platelet function and is a hereditary X-linked coagulation disorder caused by deficiency or reduced activity of Factor VIII in Haemophilia A or Factor IX in Haemophilia B.To assess the clinical profile of haemophilia patients in our region.The present study was conducted in Hematology section of Postgraduate Department of Pathology, Government Medical College Jammu. Patients of all age groups who were registered at comphrensive hemophilia care centre,Govt. medical college Jammu were included in the study for a period of one year from October 2014 to September 2015. It was a prospective study. In the present study, out of 70 cases, majority of the patients 57 (81.43%) belonged to haemophilia A (FVIII deficiency) followed by 12 (17.14%) patients of haemophilia B (FIX deficiency) and 1(1.43%) patient showed deficiency of both (FVIII/IX deficiency).Majority of the patients were of severe haemophilia, followed by moderate and mild haemophilia . Out of 70 cases, 58.58% were associated with positive family history of haemophilia .Majority of the patients (31.43%) were in the age range of 11 to 20 years followed by 25.71% patients seen in age group 21-30 years.In most of the haemophilia patients(52.86%), age of manifestation of symptoms was seen in 1-5years of age group. Most common clinical presentation was found to be hemarthosis (68.57%) followed by muscle and subcutaneous hematomas(45.71%). knee joint (61.43%) was the predominantly effected joint in haemophilia followed by elbow joint (41.43%).Haemophilias are distributed worldwide and have heterogenous presentation depending upon disease severity. Knowledge of the spectrum of presentation of haemophilia in the local population helps in early diagnosis and management planning. Keywords:Hemophilia,Haemarthrosis, Hemophilia A,Hemophilia B.
Authors and Affiliations
Sunil Kumar Raina, Bharti Devi Thaker, Arti Devi, K. K. Kaul
Keywords
Related Articles
- EP ID EP372312
- DOI -
- Views 73
- Downloads 0
Prospective study of prescribing pattern in patients with T2DM and hypertension
Abstract: Rational drug utilization must be promoted in patients with type 2 diabetes mellitus (T2DM) as it is emerging as one of the major health related issue leading to increase in rate of morbidity and mortality.The...
Correlation between Carotid Intima Media Thickness in Type Two Diabetes Mellitus with dyslipidemia in Central India
Dyslipidemia is major cause for atherosclerosis. There is synergistic effect of dyslipidemia & type II DM with carotid intimal thickening, which is self has high correlation with cardio-vascular mortality & morbidity obj...
To Decide the Management Plan of Underlying Etiology of Headache in Children
Headache is a common reason why pediatric patients seek medical care as it has a significant impact on the lives of children and adolescents, resulting in school absence, decreased extracurricular activities and poor aca...
Assessment of the Experience of Young Type 1 Diabetic during the Month of Ramadan
Abstract: Diabetes can be considered by muslim type 1 diabetics as a real burden preventing them from fasting. The main objective of our study is to study the experience of the type 1 diabetic during Ramadan. This is a l...
A Comparative Study of the Influence of Midwifery Consultation on the Knowledge and Attitude of Infertile Women with Mild to Moderate Depression Undergoing IVF
Abstract:The aim is toinvestigate that how much midwives' consultation can influence depressed infertile women's attitude and knowledge, to improve their quality of life and their probable success in their treatment. In...