CLINICAL PROFILE OF HENOCH-SCHONLEIN PURPURA IN CHILDREN
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 22
Abstract
BACKGROUND Henoch-Schonlein purpura (HSP) is the most common systemic vasculitis in children. It can produce multisystem involvement. The disease is usually self-limited, but can occasionally produce life-threatening gastrointestinal and renal manifestations. The aim of the study is to describe the age of onset and clinical profile of HSP in children. MATERIALS AND METHODS This is a retrospective descriptive study conducted in a tertiary care hospital. 61 children below 12 years who were admitted over a 2-year period with a diagnosis of HSP based on American College of Rheumatology criteria were included in the study. The clinical details were collected from the case records and entered in a proforma. Data was analysed statistically. RESULTS The mean age of presentation was 6.7 years. The male-to-female ratio was 1.2: 1. The commonest clinical features were purpura (100%), abdominal pain (70%) and arthritis (65%). Renal involvement was seen in 5%. Anaemia was seen in 48%, raised ESR in 50% and thrombocytosis in 20%. Steroids were used in treatment in 55% of patients. CONCLUSION The clinical profile of HSP in children was similar to that found in other studies except for renal involvement, which showed much lower incidence in this study. Gastrointestinal manifestations and arthritis may occasionally be the presenting features of HSP even before appearance of rash. Steroids were used in more than half of the patients with HSP.
Authors and Affiliations
Deepa Kunju Krishnan, Bindu Krishnan Padma
Keywords
Related Articles
- EP ID EP433341
- DOI 10.14260/jemds/2018/601
- Views 93
- Downloads 0
DOES UNMET NEED OF FAMILY PLANNING DIFFER IN WOMEN OF URBAN AND RURAL AREAS OF CENTRAL INDIA?
BACKGROUND Women with unmet need are those who are fecund and sexually active but are not using any method of contraception, and report not wanting any more children or wanting to delay the next child. The concept of unm...
CT EVALUATION OF ASSOCIATION BETWEEN PERICARDIAL FAT VOLUME AND CORONARY ARTERY DISEASE
BACKGROUND Pericardial fat is the adipose tissue surrounding the heart. It releases inflammatory cytokines in a local fashion and affect only the adjacent structures, which are coronary arteries. Multiple studies have tr...
DISTRIBUTION OF BLOOD GROUP IN BLOOD DONOR POPULATION IN WEST BENGAL
BACKGROUND The ABO blood group and Rh type is unique to every single individual. Prevalence of blood groups of all four types is different in various regions of this world. Aim: The present study is intended to detect th...
A PROSPECTIVE OBSERVATIONAL STUDY TO COMPARE THE ANTIEMETIC EFFICACY AND SAFETY PROFILE OF TWO COMBINATIONS NAMELY ONDANSETRON-DEXAMETHASONE VERSUS PALONOSETRON-DEXAMETHASONE IN PROPHYLAXIS OF CISPLATIN INDUCED EMESIS
BACKGROUND Chemotherapy Induced Nausea and Vomiting (CINV) are among the most distressing symptoms for cancer patients and preventing this can lead to a better treatment outcome. Serotonin (5-HT3) receptor anta...
COMPARATIVE EVALUATION OF MICROTENSILE BOND STRENGTHS OF POSTERIOR COMPOSITE WITH DIFFERENT LINERS- AN IN VITRO STUDY
BACKGROUND Aim- The objective of this study is to evaluate the bond strengths of two different liners under the posterior composite restoration. MATERIALS AND METHODS Forty-five freshly extracted human mandibular molars...