Clinical Profile of Hypoxic- Ischemic Encephalopathy in Neonates with Birth Asphyxia in a Rural Tertiary Care Hospital in Central India
Journal Title: Pediatric Education and Research - Year 2018, Vol 6, Issue 2
Abstract
Context- Perinatal asphyxia and Postasphyxial hypoxic-ischemic encephalopathy (HIE) is a major cause of early neonatal mortality in India accounting for 24.3% of neonatal deaths. Aim- To study risk factors, clinical, biochemical, Neurosonography parameters and short term outcome of neonates with HIE. Setting and Design- Study conducted at AVBRH, Sawangi (M) after seeking IEC approval. It was a prospective observational study. Material and method-All neonates delivered in AVBRH and admitted to NICU with birth asphyxia and HIE were included in the study. A detailed history, examination, HIE staging, cord blood ABG, Neurosonography, other investigations and short term outcome were recorded in prevalidated proforma and data was statistically analyzed using SPSS 22.0. Results- Incidence of Birth asphyxia was 2.97%, incidence of HIE was 1.76%. Of all neonates with HIE (study group n=50) 26% were in HIE stage I, 54% were in stage II and 20% were in stage III. On umbilical cord ABG 20% neonates had severe acidemia and 80% had moderate acidemia. Neurosonography changes were seen in 4% neonates, mortality rate was 18%. All 9 neonates who died were in HIE stage III. Conclusion-Birth asphyxia and HIE are still a major cause of neonatal morbidity and mortality. HIE stage III, severe acidemia are associated with high mortality. Preclampsia, oligohydramnios and MSAF are risk factors associated with HIE.
Authors and Affiliations
Kher Anjali M.
Keywords
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- EP ID EP582814
- DOI 10.21088/per.2321.1644.6218.6
- Views 82
- Downloads 0
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