Clinical Profile of Idiopathic Focal Segmental Glomerulosclerosis
Journal Title: Indian Journal of Emergency Medicine - Year 2018, Vol 4, Issue 4
Abstract
Background: The cause of idiopathic focal segmental glomerulosclerosis is usually not known. Most of the patients present with primary type. The main clinical feature of FSGS is nephrotic syndrome. It causes about 10 to 15% of cases of nephrotic syndrome. Its increased incidence and high rate of progression to end stage renal disease makes it us an important disease for present study. Method: Thirty five patients of biopsy proven idiopathic FSGN with biochemical and hisptopathological data have been included in this study. All patients were treated on outpatient/inpatient basis. All patients were subjected to detailed general and systemic examination. Patients who had a minimum follow up of 3 months were included in the study. Result: Males are affected more frequently than females. Males were 26 (74%) and females were 9 (26%). The most common presentation was nephritic syndrome in 27 (77%), and clinical feature was proteinuria, in all the patients, hypertension in 16 patients (46%), and hematuria in 16 patients (46%). 16 patients (46%) progressed to renal failure over a period of 1 to 6 years. Conclusion: Nephrotic range (Nephritic) Proteinuria is the main clinical feature. Response to steroids is variable and unpredictable. Prognosis is better in steroid responsive as compared to non – responsive patients
Authors and Affiliations
Nirmal B Taparia
Keywords
Related Articles
- EP ID EP553167
- DOI 10.21088/ijem.2395.311X.4418.3
- Views 96
- Downloads 0
Dramatıc Outcome of Tradıtıonal Treatment: Burn Injurıes Developed Secondary to Ranunculus Arvensıs
The plant of Ranunculus arvensis, a member of Ranunculeceae family, has been used as a traditional method in order to treat a variety of diseases such as rheumatic pain, abscess drainage, burn injuries, wounds. In this s...
Rare Presentation of Prolonged Impaction of A Button Battery in Esophagus without Life-Threatening Consequences
The diagnosis of button battery ingestion in toddler age group can be quite difficult as the patient cannot give the history himself/herself (unless it is witnessed). Such ingestion can lead to serious complications due...
Clinical Presentation of Renal Injury at a Tertiary Care Hospital
Introduction: AKI occurs predominantly in urban intensive care units and is associated with multiorgan failure and sepsis, high mortality, and occurrence in older populations. While cases of AKI in urban areas of the dev...
A study on Risk Factors Associated with Ischemic Stroke among Coronary Artery Disease Patients
Premonitory stroke symptoms are not always found; fewer than 20% of stroke patients have a prior TIA. Focal premonitory symptoms, when present, usually predate infarction rather than haemorrhage. When they occur, they ma...
Acute Myocardial Infarction Presenting with Atypical Symptoms
Introduction: Chest pain is the most common key presentation of acute coronary syndrome presenting to Emergency department. But few patients may present with atypical symptoms and pose a great challenge to the Emergency...