CLINICAL PROFILE OF RICKETTSIAL INFECTION IN VIJAYAPUR, NORTH KARNATAKA- A RETROSPECTIVE STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 22
Abstract
BACKGROUND We wanted to analyse the clinical profile of Rickettsial cases with an emphasis on epidemiology, clinical features, diagnosis and management issues of these infections, in a major tertiary referral medical college hospital in Vijayapur. METHODS We have summarized the data from 113 hospitalized patients who were laboratory confirmed for Rickettsial infection at Al Ameen Hospital, Vijaypur. Patients were treated as per recommendations of Tick-Borne Rickettsial Diseases Working Group of Centre for Disease Control (CDC), Atlanta, for management of Rickettsial infections. RESULTS 312 cases from June 2017 to December 2018 were studied retrospectively for patient’s demography, clinical presentation, treatment and outcome. Patients with history of fever of 2-4 weeks and positive Weil-Felix test, a negative malaria, chikungunya and dengue serology were diagnosed as probable rickettsial disease positive. Four patients had skin rashes. 3 persons had eschar at presentation. Number of males affected was marginally higher in number. 44 cases belonged to the rural areas surrounding Vijayapur city. No deaths were recorded. CONCLUSIONS Rickettsial fever is not a common diagnosis for fever because of nonspecific signs and symptoms, and absence of widely available sensitive and specific diagnostic tests. Failure of timely diagnosis leads to significant morbidity and mortality. Some patients with rickettsial diseases might initially receive an alternative diagnosis, and be empirically treated with antibiotics inactive against rickettsia. However, treatment for this disease is easy, affordable and often successful with good response if diagnosed with a higher index of suspicion than is being warranted at the present juncture.
Authors and Affiliations
Satish Talikoti, Nijora Deka
COMPARATIVE STUDY BETWEEN BUPIVACAINE ALONE AND BUPIVACAINE WITH FENTANYL IN AXILLARY PLEXUS BLOCK FOR UPPER LIMB SURGERIES
BACKGROUND The addition of adjuncts like Neostigmine, opioids, midazolam, dexmedetomidine, hyaluronidase, clonidine etc., to local anaesthetics for brachial plexus block may enhance the quality and duration of analgesia....
SOLITARY TRICHOEPITHELIOMA– A CASE REPORT
PRESENTATION OF CASE An 80-year old man presented to our outpatient department with a solitary swelling on the lateral aspect of his right lower lid. The swelling had appeared 5 years ago and was progressively increasing...
A STUDY OF BACTERIOLOGICAL PROFILE AND ANTIMICROBIAL SPECTRUM OF DIABETIC FOOT ULCER
BACKGROUND There are various pathophysiological factors, which along with hyperglycaemic state is responsible for diabetic foot ulcer. Out of these, there are three important components, which play important role that is...
STUDY OF NEUTROPHIL NUCLEAR LOBULATIONS ON PERIPHERAL BLOOD SMEARS AND DISTINGUISHING THE BILOBED NEUTROPHILS FROM PELGER HUET CELLS
BACKGROUND Myeloid cells in the peripheral blood are classified into neutrophils, eosinophils and basophils depending on the staining characteristics of the cytoplasmic granules.1 Neutrophils are lobulated granulocytes....
GIANT PROSTHETIC VALVE THROMBUS
Mechanical prosthetic valves are predisposed to bleeding, thrombosis & thromboembolic complications. Overall incidence of thromboembolic complications is 1% per year who are on oral anticoagulants, whereas bleeding compl...