Clinical significance of repolarization parameters in Brugada Syndrome patients
Journal Title: Kocaeli Tıp Dergisi - Year 2017, Vol 6, Issue 3
Abstract
INTRODUCTION: Brugada syndrome (BS) is a genetic disease with increased risk of sudden cardiac death. Increased T wave alternans (TWA) and prolonged T wave peak to end (Tp-e) interval are linked to sudden cardiac death. In the present study, we investigated the role of TWA and Tp-e interval in BS. METHODS: Thirteen BS and 11 controls were included. TWA and ECG were recorded. Patients and controls were followed for ventricular arrhythmias. RESULTS: TWA study was negative in BS and controls. Tp-e interval was longer in BS than controls. Furthermore, during f/u all patients with ventricular arrhythmiashad Tp-e interval longer than 100 ms. DISCUSSION AND CONCLUSION: TWA is an inappropriate test for BS, prolonger Tpe may be related to increased risk in BS patients.
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