Clinical Spectrum of Presentation of Obstructive Jaundice in Inflammation, Stone Disease, and Malignancy
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 4
Abstract
Introduction: The initial evaluation of obstructive jaundice involves distinguishing intrahepatic and extrahepatic biliary obstruction. Clinical data such as history, physical examination, and laboratory tests have been shown to accurately identify up to 90% of patients whose jaundice is caused by extrahepatic obstruction. Aim: The aim of the study is etiological spectrum, treatment outcome of obstructive jaundice. Materials and Methods: This prospective observational study was conducted in the Department of General Surgery, Tirunelveli Medical College Hospital. Patients of any age or sex admitted with complaints of jaundice, clinically and biochemically diagnosed to have obstructive jaundice were included in the study. Results: Choledocholithiasis accounts for about 22% of the overall etiology of obstructive jaundice and about 73.3% of the benign causes. Periampullary carcinoma appears to be the most common cause accounting for 34% of malignancies. Mortality due to the disease is 3% morbidities are 6% in overall population included in the study. Most of them who had malignant cachexia also had ascites. Conclusion: The most common benign etiology was choledocholithiasis. Ultrasonography of the abdomen is very accurate in diagnosing the presence of obstruction to the biliary tree, easily available, and cost-effective but operator dependant. Computed tomography abdomen is reliable in confirming the diagnosis and determining the level of obstruction.
Authors and Affiliations
R Selvasekaran, G Nagalakshmi, Heber Anandan
Keywords
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