Clinical Spectrum of Severe Plasmodium falciparum Malaria in a Tertiary Care Centre of Eastern India
Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2016, Vol 12, Issue 4
Abstract
Introduction: Plasmodium falciparum malaria is one of the major public health problem presented with varied clinical severity. This study was carried out to observe the clinical spectrum of severe falciparum malaria in a tertiary health care centre. Methods: This study was undertaken in hospitalized adults with suspected severe malaria. Confirmation of falciparum infection was done by ICT/QBC and single-step-PCR. Diagnosis of severe malaria was done by WHO- guideline 2010. Results: 450 adult cases with falciparum infection were studied. Maximum number of cases was from 15-25 years age group depicting the high exposure to malaria. In these patients, acute renal failure (ARF) was the most common (36.2%) complication followed by cerebral malaria (35.3%), jaundice (27.8%), hepatic dysfunction (21.8%), respiratory distress (18.4%), severe malarial anemia (15.8%), thrombocytopenia (15.1%), and hypoglycemia (9.3%). Mortality was found in 6.0% of cases. Cerebral involvement and ARF were the common cause of death in these patients. Conclusion: ARF is the most common type of clinical severity followed by cerebral malaria in adults and both are equally responsible for death along with other complications. Looking into the matter of varied clinical severity, accurate diagnosis, effective anti-malarial treatment along with supportive therapy is necessary to triumph over this deadly severe falciparum malaria.
Authors and Affiliations
Prasanta Purohit, Pradeep Kumar Mohanty, Siris Patel, Snehadhini Dehury, Satyabrata Meher, Kishalaya Das, Ashutosh Rath, Jagannath Hati, Ashok Kumar Behera
Assessment of Training on Acute Flaccid Paralysis Surveillance among Surveillance Officers in Ondo State, Nigeria
Aim: We assessed the immediate impact of Acute Flaccid Paralysis (AFP) surveillance training on the knowledge of AFP surveillance among AFP surveillance personnel, and identify factors associated with changes in knowledg...
Safety Precaution; Knowledge, Attitude, Practice and Sociodemographic Determinants among Health Care Workers at Primary Health Care Level in Enugu State, Nigeria
Aim: This aims to explore the knowledge, attitude, practice and sociodemographic determinants of Safety Precaution (SP) among Health Care Workers (HCWs) at Primary Health Care level. Study Design: Descriptive cross secti...
Living with Obstetric Fistula: Perceived Causes, Challenges and Coping Strategies among Women Attending the Fistula Clinic at Mulago Hospital, Uganda
Aims: To determine perceived causes, challenges and coping mechanisms of women living with obstetric fistula (OF) in Uganda. Study Design: Cross-sectional study. Place and Duration of the Study: Mulago National Referra...
Promotion of Health in Self-efficacy, to Reduce Tobacco Consumption in Young Adults
Aim: The objective was determinate the effect of intervention on the self-efficacy and tobacco intake, to decrease smoking in young adults. Study Design: Study interventional. Place and Duration of the Study: Juventino...
Malaria Prevalence, the Use of Intermittent Preventive Therapy and Long Lasting Insecticidal Nets among Pregnant Women in Onitsha, Anambra State, Nigeria
Malaria prevalence, the use of intermittent preventive therapy (IPT) and long lasting insecticidal nets (LLINs) was studied among pregnant women in Onitsha, Anambra State, Nigeria. Peripheral blood were obtained from 204...