CLINICAL STUDY ON PREVALENCE AND PATTERN OF DYSLIPIDEMIA IN TYPE 2 DIABETES MELLITUS PATIENTS IN A TERTIARY TEACHING HOSPITAL OF NORTH EAST INDIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 29
Abstract
BACKGROUND Diabetes mellitus (DM) is a common secondary cause of dyslipidaemia, particularly if glycaemic control is poor, and can be an important risk factor for atherosclerosis and coronary artery disease and that can be a major cause of morbidity and mortality in diabetic patients. Our aim was to determine the prevalence and pattern of dyslipidaemia in patients with type 2 DM in this region. METHODS This study was carried out among 200 type 2 diabetic patients attending the Diabetic Clinic and indoor medicine department, North Bengal Medical College and Hospital, Darjeeling. Patients suffering from other known cause of secondary dyslipidaemia were excluded. Each patient’s lipid profile and HbA1c results were estimated. The lipid profile included total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Patients with one or more of the above parameters outside the targets recommended by the National Cholesterol Education Programme (NCEP) guidelines were considered to have dyslipidaemia. RESULTS Of these 200 type 2 DM patients studied, 110 were male and 90 were female. The most prevalent lipid parameter not at target was triglyceride >150, HDL (<40 in male, <50 in female an LDL-C of ≥130 mg/dl in nearly 80% of patients). The most common pattern of dyslipidaemia was hypertriglyceridemia, low HDL and combined dyslipidaemia. No significant relationship was found between HbA1c and any of the lipid parameters. CONCLUSIONS The vast majority of the type 2 diabetic patients studied had dyslipidaemia. Dyslipidaemia as a metabolic abnormality is frequently associated with diabetes mellitus and is a strong clustering risk factor for coronary artery disease in diabetic subjects. Measures should aim at controlling dyslipidaemia and at reducing the burden of coronary artery disease.
Authors and Affiliations
Achintya Narayan Ray, Narayan Pandit
Keywords
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- EP ID EP670349
- DOI 10.18410/jebmh/2019/402
- Views 59
- Downloads 0
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