Clinical Utility of 10% Dextrose Solution as Analgesic after DPT Vaccination and it Comparison with Direct Breastfeeding
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 1
Abstract
Objective: To compare analgesic effect of 10% dextrose solution with direct breast feeding, and placebo after DPT vaccination to 6week- 3month old infants. Participants and study Design: Infants coming for their DPT vaccination were randomized in to three groups of 50 each in a randomized, placebo controlled trial. Outcome Measures: The primary outcome variable was the duration of cry after vaccination. Secondary outcome variables were Modified Facial Coding Score (MFCS) and latency of onset of cry. Results: 150 babies were equally in enrolled in breast feed group,10% dextrose fed group and distilled water fed group. Median duration of cry was significantly lower in direct breastfed 35.5(17-54)seconds and 10%dextrose fed babies52.5(31-67.5)seconds as compared to babies given distilled water 81.5(33.5-119.5) seconds (P<0.05). Conclusion: Direct breasting and 10% dextrose act as analgesic in young infants undergoing DPT vaccination in young infants less than 3 months of age
Authors and Affiliations
Yogesh Yadav
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