CLINICO-EPIDEMIOLOGICAL PROFILE OF ACUTE WATERY DIARRHOEA IN UNDER FIVE CHILDREN WITH SPECIAL REFERENCE TO ROTAVIRUS INFECTION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 14
Abstract
BACKGROUND Diarrhoeal disorders in childhood accounts for a large proportion (9%) of childhood deaths with an estimated 0.71 million deaths per year globally, making it the second most common cause of child deaths worldwide. In early childhood, the single most important cause of severe dehydrating diarrhoea is rotavirus infection. We wanted to identify cases of rotavirus among children less than five years of age hospitalized for acute watery diarrhoea and to determine the circulating rotavirus genotypes and to identify any seasonal variation in rotavirus infectivity. METHODS A prospective observational study was conducted in MY hospital Indore over a period of 15 months, during which, 295 children aged less than 5 years who were admitted with acute watery diarrhoea were enrolled, their stool samples collected, and analysed, for rotavirus genotype. RESULTS Rotavirus positive diarrhoea cases were 74 out of total 295 children enrolled, of which 44 positive cases were aged less than 1 year. 40 positive cases were reported in the winter months of October to January. CONCLUSIONS Prevalence of rota viral diarrhoea in our study is 25%. Most common age group affected by rotavirus is less than one year. Rotavirus infection is more common in the winter season. Most common genotype of rotavirus causing diarrhoea in our setting is G3P8
Authors and Affiliations
Prakhar Nyati, Prachi Choudhary, Sharad Thora
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