Clinico-epidemiological profile of hemophilia patients in north India: An observational study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Objective: To describe the clinical and epidemiological profile of hemophiliac patients in north India. Materials and Methods: This was an observational cross-sectional study. Patients of all age groups with hemophilia registered under department of Medicine were included. A detailed clinical history was elicited from the accompanying parent/guardian. Patients were further classified into mild, moderate, severe depending on lab records and factor VIII and IX assay levels. Results: Out of the total 115 hemophilia patients, 108 patients were of hemophilia A and 7 of hemophilia B. 54.78% (63/115) were >18 years of age. Mean age of patients was 26.15 years. Majority of the patients had severe hemophilia i.e. 66% (76/115), 20.86% (24/115) had moderate disease while 13% (15/115) had mild form of the disease. Knee joint was observed to be as the target joint among 31.81% of the patients. In patients with severe form of hemophilia A, 49 out of 71 required regular replacement of factor VIII making it about 69% and 5 out of 7 required regular replacement of factor IX making it 57.14%. Conclusion: The severe type of haemophilia type A was more common than mild and moderate types. The study also emphasizes the need to identify hemophilia as a disease of national concern and to initiate a national programme for diagnosis, prevention, care and support for hemophilia.
Authors and Affiliations
Jasbir Singh, Ankur Chaudhary, Sumit Yadav, Deepinder Singh, Raminder Pal Singh Sibia
Keywords
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- DOI 10.9790/0853-1801151015.
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