Clinico-Metabolic profile of Xanthelasma palpebrum
Journal Title: IP Indian Journal of Clinical and Experimental Dermatology - Year 2018, Vol 4, Issue 1
Abstract
Introduction Xanthelasma palpebrum XP is a disorder of lipid metabolism that usually presents as bilateral and symmetrical soft velvety papules and plaques around the eyelids Though various factors contribute to its etiology a strong association with lipid metabolism is proposed Usually seen in middle age people its main concern is cosmetic appearanceObjective 1 To evaluate the lipid profile glycemic levels Body Mass Index BMI in patients with Xanthelasma palpebrum 2 To find the association between parameters like age sex and comorbid illness with Xanthelasma palpebrumMaterials and Methods This prospective study included 42 clinically diagnosed patients with Xanthelasma Palpebrarum and 95 subjects in control group with noninflammatory skin disorders Levels of serum triglyceride cholesterol HDL LDL VLDL blood sugar fasting and post prandial were determined in all cases along with body mass index and blood pressure These parameters were compared in both groups and association with XP was analysedResults and Discussion In our study XP was more common in females compared to males In our study of patients with XP average fasting blood sugar was 108 gm and average post prandial blood sugar was 152gm Average serum triglyceride levels in patients with XP was 1714 mgdl compared to 1084 mgdl in control group with significant p value ie 0001 suggesting strong correlation between XP and serum triglyceride levelsConclusionnbsp Patients with XP usually visit doctor with cosmetic concern In most of the cases of XP serum cholesterol triglyceride and VLDL levels are deranged Patients with XP should be evaluated for above parameters and systemic management done along with treatment of XPKeywordsnbspnbspXanthelasmanbsp Palpebrum XP Low Density Lipoprotein LDL High Density Lipoprotein HDL Very Low Density Lipoprotein VLDLnbsp Body Mass IndexBMI Diabetes Mellitus DM
Authors and Affiliations
Savita Chaudhary, Samreen Haque
Keywords
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- EP ID EP488944
- DOI 10.18231/.2018.0005
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