Clinico - mycological study on superficial fungal infections in tertiary care hospital and a profile of their antifungal susceptibility pattern
Journal Title: Indian Journal of Microbiology Research - Year 2017, Vol 4, Issue 2
Abstract
Background: Superficial fungal infections are one among the most common fungal diseases in the world. Dermatophytosis is common in tropical countries like India and may reach epidemic proportions in areas with high rate of humidity and over population and poor hygienic conditions. Material & Method: The present study was undertaken to isolate, identify and determine the antifungal susceptibility of various fungal agents causing mycoses among the patients attending the Dermatology outpatient (OP) Chettinad hospital and research institute. Clinical samples from 200 patients were subjected to KOH examination and culture isolation. Causative agents were identified by colony morphology, pigment production and by microscopic examination. Antifungal susceptibility testing was done by broth dilution detecting the minimum inhibitory concentration. Result: In total of 200 specimens cultured 98 dermatophytes were isolated and 12 non dermatophytic fungus were isolated which includes 5 isolates of Candida albicans and 7 isolates of Candida non albicans. Trichophyton mentagrophyte was the predominant dermatophyte isolate found in 62 cases of dermatophytosis followed by T.rubrum 22. This study showed among 98 isolates of dermatophytes, lowest value of MIC sensitivity was recorded in terbinafine as 0.03μg/ml and highest value was recorded with fluconazole 32μg/ml. Conclusion: It is concluded that causative fungal agent for cutaneous mycoses in addition to dermatophytes and non-dermatophytes fungi Candida species also play an important role. Terbinafine was found to be the most potent drug for treating dermatophytic infections.
Authors and Affiliations
Kumaran Ganesan, AS Shameem Banu, Riswana Jasmine
Keywords
Related Articles
- EP ID EP294680
- DOI 10.18231/2394-5478.2017.0035
- Views 60
- Downloads 0
Dermatophytoses; epidemiology and distribution among urban and sub urban population
Background: Superficial mycoses or superficial cutaneous fungal infections are the most common mycotic infections worldwide, which involve outermost covering of skin and its appendages like hair and nail. The patients in...
Prevalence of Clindamycin resistance among Staphylococcus aureus in a tertiary care hospital in South India
Background: Staphylococcus aureus, a pyogenic bacterium, causes a wide spectrum of diseases, ranging from minor skin infections to fatal necrotizing pneumonia. The emergence and spread of MRSA (Methicillin Resistant Stap...
Serological and haematological profile for early diagnosis of dengue infection in tertiary care hospital
Context: Dengue is a major public-health concern throughout tropical and subtropical regions of the world including India. All four serotypes of the dengue can produce wide range of the symptoms from mild clinical diseas...
Community acquired urinary tract infections (CAUTI) with special reference to antibiogram of Escherichia coli and Klebsiella species
Aim: Escherichia coli and Klebsiella species are the most important uropathogens. The present study was undertaken to isolate uropathogens causing community acquired urinary tract infections (CAUTIs) and their antibiogra...
Comparison of staining techniques– Ziehl Neelsen stain, Gabbet’s Stain, Fluorochrome stain for detection of mycobacterium tuberculosis in sputum
In developing countries ZiehlNeelsen ZN sputum smear microscopy is widely usedThe present prospective study was under taken to see the efficacy of ZiehlNeelson method versus Gabbett and Fluorescent staining in the detect...