Clinico-Pathological Analysis of Granular Cell Tumor: Study from a Tertiary Care Centre
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 3
Abstract
Background: Granular cell tumor is an uncommon benign tumour mainly occurring in skin, tongue, oral cavity as a solitary nodule. It presents as a painless soft to firm subcutaneous nodule and can be diagnosed after histological examination. It has uncertain histogenesis. Recent ultrastructural stains like S-100, Neuron Specific Enolase have confirmed its derivation from Schwann cells and peripheral nerves. Material and Methods: This study was conducted in S.C.B. Medical College, Cuttack over a period of two years from January 2015 to December 2016. All the cases presenting as nodules over skin and mucosa subjected to histopathological examination were analysed. Out of these, the cases of granular cell tumors were included in the study. Different variables like age, sex, clinical details, cytology, histopathology and immunohistochemical status were recorded and analysed. Results: Out of total 206 cases of tumor and tumor like lesions of skin and mucosa, there were total six cases of GCT. The mean age of presentation was 37 years, affecting all male patients and involving different sites of body. All of them were benign without history of recurrence. Conclusion: This study suggests that GCTs are mostly benign tumors usually affecting males with a prolonged course. Majority of the tumors were positive for S-100 protein supporting the hypothesis of it’s origin from Schwann cells.
Authors and Affiliations
Asaranti Kar, Goutami Das Nayak, Pranati Pradhan, Debahuti Mohapatra, Sandeep Mohanty, Shushruta Mohanty
Keywords
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- EP ID EP547780
- DOI 10.21276/ijmrp.2017.3.3.010
- Views 94
- Downloads 0
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