Clinico-pathological profile of primary lung cancer in a tertiary care center in South India
Journal Title: IP Indian Journal of Immunology and Respiratory Medicine - Year 2018, Vol 3, Issue 4
Abstract
Background Lung is one of the commonest site for malignant neoplasms both primary and metastatic Primary lung malignancies are presently heading the list of common cancers worldwide and accounts for more death than any other cancer In lung cancer diagnosis of histological type is of great significance to determine the prognosis and for planning the treatment Radiology and imaging plays an integral part in diagnosis management staging and followup of lung cancer patients Moreover radiology can give vital clues towards histological diagnosis of the malignancy Our study aims to analyse the clinical radiological and histological patterns occurring in patients with primary lung cancerMaterials and Methods A total of 116 patients with clinical and radiological features suggestive of primary lung cancer were enrolled Diagnosis of lung cancer was established histopathologically Clinicopathological profile and histopathological analysis was done individually for all patientsResults Our study included a total of 116 cases with 84 males 72 and 32 28 female patients with a median age of 60 years range 1990 years The most common histological type of lung cancer was adenocarcinoma in 796982 of patients followed by squamous cell carcinoma in 22 patients 1896 Adenocarcinoma was the most common type among both males and females Also adenocarcinoma was the commonest histological pattern among nonsmokers The most common clinical presentation was cough with expectoration Radiologically most common feature was mass lesion 862 Seventy four patients 6378 with nonsmall cell lung cancer had metastatic disease the most common being malignant pleural effusion Six out of seven patients of small cell cancer had extensive stageConclusions Adenocarcinoma is the commonest histological pattern of lung cancer even in smokers Lung cancer is not necessarily a disease of old age Majority of the patients still present in advanced stages A good screening method for lung cancer is the need of the hourKeywords Adenocarcinoma Primary lung cancer Pathological profile
Authors and Affiliations
Vishnukanth Govindaraj, Rajkrishnan Soman, Vinodkumar Saka, Bhavana Badhe, Biswajit Dubashi
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