Clinico-Serological profile of Acute Sporadic Viral Hepatitis in Kashimiri Adults: Hospital based Prospective Study
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 12
Abstract
Background: There is no report on clinico-serological profile of acute viral hepatitis from the state of J & K since the discovery of hepatitis E and hepatitis C. Methods: A prospective hospital based study was conducted in a large referral hospital in Kashmir India. 56 consecutive patients with acute viral hepatitis were studied for their presentation, etiology and clinical features. Results: Acute viral hepatitis was more common in males with MF ratio of 1.33:1. Forty (71.4%) belonged to rural and 16(28.57%) to urban areas. Most commonly involved age group was 21-30 years (37%) followed by 14-20 years (25%) . Most commonly observed symptoms were Jaundice (82%), Anorexia (76.8%), and dark urine (73.2%). Only 7% patients had cholestatic features. 5.4% patients had anictric hepatitis. Hepatomegaly was observed in 68.8% and splenomegaly in 19.6%. Clinical and biochemical characteristics were not helpful in differentiating various types of hepatotropic viral hepatitis. Most common viral infections was hepatitis E(50%), followed by hepatitis B(26.7%), hepatitis A(16%), hepatitis C (3.5%) and dual infection of hepatitis A and E in(3.5%). Conclusion: Acute viral hepatitis is an important public health problem in developing countries. Most cases are due to hepatitis E, and hepatitis A continues to be an important cause of acute viral hepatitis in developing countries even in adults. Clinical and biochemical characteristics were not helpful in differentiating different types of hepatotrophic viral hepatitis.
Authors and Affiliations
Nisar Ahmad Shah
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