CLINICOHEMATOLOGICAL PROFILES OF HEPATITIS B VIRUS (HBV): OBSERVATIONS FROM A TERTIARY CARE CENTRE
Journal Title: International Journal of Medical Laboratory Research - Year 2018, Vol 3, Issue 3
Abstract
Aim: In humans, Hepatitis B virus(HBV) is arguably the most common organ specific virus affecting the liver. The pathological sequelae and stages especially in the liver are well studied. However reports on the effect of HBV on the extrahepatic organs are lacking. The present study was carried out to ascertain clinical presentations and the alterations on the haematological and hepatic parameters. Material and Methods: This was a retrospective study and was conducted in a tertiary care hospital in India. Data was collected and analyzed in people who were confirmed to be affected only by HBV by the standard diagnostic method using the HB surface Antigen (HBsAg) for the period January 2016 to December 2016. Results: The results indicated that during the study period, a total of 233 people were included in the study and compared with healthy individuals who were coming for regular health check up and were tested negative for any infectious and chronic diseases. Of these 46 were symptomatic, while 187 were asymptomatic and were diagnosed incidentally during routine/mandatory investigation before surgery. In the 46 symptomatic patient’s fever (73.91%), jaundice (63.04%), loss of appetite (39.12%), nausea & vomiting (52.17%), fatigue (28.26%), abdominal pain (17.39%) and Ascites (8.69%) were seen. There was a significant difference in the various haematological, hepatic and electrolyte endpoints (p < 0.05 to 0.0001). Conclusion: The study indicates that acute infection with HBV causes changes in the alterations in haematological, hepatic and electrolytes in the serum.
Authors and Affiliations
Ramakrishna Pai Jakribettu
Keywords
Related Articles
- EP ID EP426841
- DOI -
- Views 100
- Downloads 0
KIDNEY FUNCTIONS IN WISTER RATS TREATED WTH ARTESUNATE AND AMODIAQUINE
Malaria is a mosquito bone disease caused by plasmodium parasite. Several drugs have been developed and used in treatment of this disease but, many of these medications results in adverse side effects. This study evaluat...
IMMUNOHISTOCHEMICAL CORRELATION BETWEEN THE EXPRESSION OF VITAMIN D RECEPTOR (VDR) AND ESTROGEN RECEPTOR (ER) IN INVASIVE DUCTAL CARCINOMA TISSUES
Aim: The study was carried out to determine the Immunohistochemical Correlation between the Expression of Vitamin D Receptor (VDR) and Estrogen Receptor (ER) in Invasive Ductal Carcinoma (IDC) tissues Materials and Metho...
QUALITATIVE AND QUANTITATIVE ANALYSIS OF BILIARY CALCULI IN A TERTIARY CARE HOSPITAL
Background :- Gallstone disease remains a serious health concern for human beings, affecting millions of people throughout the world. Material and method:- The cross sectional study was conducted in department of Biochem...
URINE CYTOLOGY AMONG HIV-SEROPOSITIVE PERSONS
Human Immunodeficiency Virus (HIV) infection and the use of antiretroviral therapy (ART) are risk factors in the development of urinary system neoplasia. In this study, the urine smears of HIV-seropositive persons were s...
INCIDENCE OF NAUSEA AND VOMITING IN CANCER PATIENTS UNDERGOING CHEMOTHERAPY OR RADIOTHERAPY: OBSERVATIONS FROM SUPER-SPECIALITY HOSPITAL
BACKGROUND: Nausea and vomiting is a debilitating side effect in the treatment of cancer with chemotherapy and radiotherapy. At times this also affects the planned treatment schedule and the outcome. The present study wa...