Clinicopathological Conference Report
Journal Title: Journal of Postgraduate Medicine Education and Research - Year 2017, Vol 51, Issue 3
Abstract
Primary amenorrhea may be due to various causes and during its workup, if gonadotropin levels are increased, it is diagnosed as hypergonadotropic hypogonadism. The next step is to check for a Y chromosome by doing a karyotype as many of such “women” will be having an XY karyotype and hypergonadotropic hypogonadism due to gonadal dysgenesis. They have an over 25% chance of having a germ cell tumor in the dysgenetic gonads, which should be removed after pubertal development has occurred
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