CLINICOPATHOLOGICAL PATTERNS OF CUTANEOUS METASTASES- A SEVEN-YEAR STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 25
Abstract
BACKGROUND Cutaneous metastases are rare and occur in only 0.6%-10.4% of all malignancies.1,2 Though they are more often seen in the advanced stage of cancer, it may be the first sign of malignancy and can lead to diagnosis of the primary tumour. The magnitude and distribution of cutaneous metastases in North Kerala is not well known. We aimed to categorize the different primaries of the skin metastases and study the demographic and clinicopathological characteristics of cutaneous metastases. METHODS All cases of cutaneous metastases diagnosed either by histopathology or Fine Needle Aspiration Cytology (FNAC) in the Department of Pathology, Government Medical College, Kozhikode, during the seven-year period between October 2010 and September 2017 were studied. Data was retrieved from case records and analysed with the help of computer software SPSS. RESULTS Of 125 cases of cutaneous metastases, 74 cases were diagnosed by FNAC and 51 by histopathology. Most common metastatic deposits were adenocarcinoma (73.6) and squamous cell carcinoma (12%). Primary was unknown in 28.8% cases. The most common primary tumours in males were lung, hepatobiliary system, gastrointestinal (GIT) system and head & neck. In females; breast, genital system, lung, hepatobiliary and GIT were the common primaries. The commonest site of skin deposits was the chest wall. Other common sites included abdominal wall and scalp/head. CONCLUSIONS Skin is an important site of metastatic disease, particularly in patients with carcinoma of breast, lung, hepatobiliary and gastrointestinal systems. FNAC is a rapid and easy technique to diagnose skin metastases. Immunohistochemistry is an efficient ancillary aid in the detection of its origin.
Authors and Affiliations
Saji Francis, Cherukattil Hazeena, Sathi P. P
Keywords
Related Articles
- EP ID EP668382
- DOI 10.18410/jebmh/2019/352
- Views 84
- Downloads 0
A STUDY OF SURGICAL MANAGEMENT OF VOLAR BARTON’S FRACTURES USING ELLIS PLATE
BACKGROUND The distal end of radius fractures continue to pose a therapeutic challenge. Post-traumatic osteoarthrosis decreased grip strength, and endurance, as well as limited motion and carpal instability, are the comp...
PROFILE AND SHORT-TERM OUTCOME IN ADULT PATIENTS WITH NEW-ONSET SEIZURES
BACKGROUND The annual incidence is 85 per 1,00,000 for people aged 65-69 years and 135 per 1,00,000 for those aged over 80 years. Epilepsy in older patients poses several additional problems for the provision of services...
MAGICO-RELIGIOUS BELIEF IN PSYCHOSIS
BACKGROUND Magico-religious beliefs are widely prevalent in India and eastern countries compared to western countries. This causes the patients and their families spending extra ordinary time, money and effort in seeking...
NEAR MISS CASE OF HUS ASSOCIATED WITH IGA NEPHROPATHY IN PREGNANCY
BACKGROUND Glomerular disease in pregnancy should be planned in patients who are in remission to decrease fetomaternal complications. Renal diseases can masquerading as preeclampsia at presentation. A renal biopsy is par...
COMPARISON OF E-LEARNING AND CONVENTIONAL BED SIDE TEACHING FOR MEDICAL STUDENTS IN OPHTHALMOLOGY
BACKGROUND E-learning is a system of learning where the content is delivered electronically. E-learning involves using computers or IT for delivery of at least some part of the content. The objectives of the study were1....