Clinicopathological profile of malaria in Bareilly
Journal Title: International Journal of Medical Science and Public Health - Year 2017, Vol 6, Issue 9
Abstract
Background: Malaria is the major cause of infectious disease death in India. Plasmodium vivax (PV) is the most common cause of malaria among humans affecting about 25 billion population worldwide. India is having 80% of malaria cases among South East Asia region. India being the country having different geographical regions and climate, the pattern of malaria vary with places. Objectives: This study was done to study the clinical features, diagnosis, laboratory investigations, outcome, and complications of malaria in a tertiary care hospital of Bareilly. Materials and Methods: A prospective analysis of adult patients suffering from malaria was carried out during the year 2014-2015. Diagnosis of the patients was done on clinical features, peripheral smear examination, and rapid diagnostic test. The parasitic count was done from peripheral blood smear. The clinical features, laboratory investigations, treatment, and outcome were studied. The response to treatment was determined on the basis of improvement of clinical features and repeated peripheral blood smear examinations. Results: Out of the 126 patients, 71 (56.34%) were males and 55 (43.65%) were females in the age group of 15-70 years. Fever was universal presentation (P < 0.001). 47.6% of the patients complained of headache, 29.36% had vomiting. Jaundice was observed in 20.63% patients. Anemia was present 53.17%. All above results were statistically significant. 15.87% presented with loss of sleep, 7.93% as acute abdomen, 4.76% as convulsion, and 3.96% as bleeding as a result of thrombocytopenia (statistically non-significant). Among 126 malaria cases, 62 (49.2%) were with PV, 36 (28.57%) with Plasmodium falciparum, and 18 (14.28%) had mixed infection. 10 were smear negative patients, and they received empirical treatment on the basis of sign and symptoms of malaria. Conclusion: Majority of hospitalized patients were vivax positive. Complicated malaria was seen with Falciparum infection. Clinical symptomatology without blood smear positivity can be the basis of starting treatment. Epidemiological survey for drug resistance should be considered while planning an antimalarial strategy.
Authors and Affiliations
Purnima Mittra, Manmohan Krishna Pandey
Keywords
Related Articles
- EP ID EP331987
- DOI 10.5455/ijmsph.2017.0616318062017
- Views 76
- Downloads 0
Cross-sectional study for assessment of quality of life of AIDS patients attending link ART centers in relation to their age and marital status, in Haryana
Background: The number of HIV/AIDS patients is increasing worldwide. Development of various tests and antiretroviral therapy has increased the survival of these patients, but their quality of life still remains a maj...
Effect of extremely low frequency electric field on liver, kidney, and lipids of Wistar rats
Background: Increased utilization of electricity and rapid urbanization has caused a greater part of the community to be exposed to extremely low frequency (ELF) fields. Detrimental effects of power frequency fields...
Assessment of knowledge about the role of diet regime and physical exercise to control diabetes among type 2 diabetic patients in Khartoum State, Sudan
Background: Non-communicable diseases, particularly diabetes mellitus, represent a global worldwide threat, being highly prevalent and cause a wide range of disabilities, morbidity and mortality. Aims & Objec...
Mass drug administration coverage evaluation for elimination of lymphatic filariasis in Chhatarpur district of Madhya Pradesh
Background: Mass drug administration (MDA) means administration of diethylcarbamazine (DEC) tablet to all people (excluding children <2 years, pregnant women, seriously ill persons) in endemic areas once in a ye...
KAP study of reproductive health and sexually transmitted diseases among high school girls of Vadodara city
Background: Sexually transmitted diseases (STDs) are a major public health problem not only in India but all over the world. The World Health Organization (WHO) estimates that 150–300 million new cases of curable STD...