Clinicopathological Spectrum of Pancytopenia in Tertiary Care Centre in Northern India
Journal Title: RECENT ADVANCES IN PATHOLOGY AND LABORATORY MEDICINE - Year 2018, Vol 4, Issue 3
Abstract
Introduction: The term pancytopenia refers to a reduction in all three formed elements of blood-erythrocytes, leucocytes and platelets. It is not a disease entity, but rather a triad of findings that may result from a number of disease processes. The causes of pancytopenia vary depending on multiple factors. This prospective study was conducted to find out various causes of pancytopenia and their relative frequencies in a tertiary care hospital in northern India. Methods: In the present study, 60 cases were taken up for a period of 2 years at a tertiary care hospital in Northern India. The study was composed of a brief work up of history, general and systemic examination and complete hematological work up. All the data was compiled and a final diagnosis was made. Results: The age of the patients varied from 6 months to 70 years consisting of 34 males (57%) and 26 females (43%). Megaloblastic anemia was the most common cause (66.7%) followed by aplastic anemia (19%) and malignancies (6.7%). Infections and parasitic infestations accounted for the rest. Conclusion: In our study, more than 50% of the cases are due to megaloblastic anemia prevalent due to dietary deficiency & malnutrition. Also, infections and infestations (Tuberculosis, malaria, kalaazar and typhoid) should be kept in mind as a differential diagnosis of pancytopenia.
Authors and Affiliations
Dr. Karsing Patiri
Keywords
Related Articles
- EP ID EP396580
- DOI 10.24321/2454.8642.201810
- Views 53
- Downloads 0
Analysing Turnaround Time in Laboratory - A Key Performance Indicator
Background: Turnaround time (TAT) is one of the key indicators of performance of a laboratory. Laboratories define it as the time from the receipt of sample/ specimen to the reporting. A fast TAT helps clinicians in maki...
A Study to Correlate Endometrial Hyperplasia with Ovarian Stromal Change
Background: Endometrial hyperplasia in peri-menopausal age group is frequently encountered as a result of unopposed excess estrogen action, exact source of which is still debatable. Possible source is ovarian stroma. The...
HLA A24 Associated Tumor Immunity in HER2/neu Positive Breast Cancer
Breast carcinoma is the most common tumor in women and it has resulted in significant morbidity and mortality. Recognition of tumor-associated antigens (TAA) by HLA class I-restricted CD8+ T cells is fundamental for the...
Diagnostic Accuracy of USG-Guided FNAC in Gall Bladder Mass
Introduction: Malignancy of gall bladder is quite common. However, it cannot always be diagnosed only by clinical history and examination. We have evaluated diagnostic accuracy of USG-guided FNAC in GB mass.
Study of Effect of Alcohol on the Microscopic Analysis of Semen
Background: Consumption of alcohol is a major modifiable, rather avoidable lifestyle choice and has shown to affect male fertility. Alcohol has shown to cause various deleterious effects on the male reproductive system....