Clinicopathological Study of Lower Gastrointestinal Tract Lesions in Per Rectal Bleeding Cases

Abstract

Background: Rectal bleeding occurs in 20% of population in India. Rectal bleeding is mainly a manifestation of lower gastrointestinal tract lesions, which means bleeding from a site distal to ligament of Treitz, including anal canal. Though it is a common symptom in the general population, the definitive diagnosis can not be arrived on clinical and radiological basis. Clinicopathological study plays an important role in the early diagnosis and proper management of cases of colonic lesions. Aim and Objectives: To study the histopathology of various lower gastrointestinal tract lesions in patients presenting with per rectal bleeding. To categorize different lower gastrointestinal tract lesions leading to per rectal bleeding and assess their proportions into Nonneoplastic and Neoplastic. To correlate the clinicopathological findings with age, sex, site of lesion, radiological & endoscopic findings. Materials and methods: A cross sectional prospective study on the histopathology of lower gastrointestinal tract lesions in 40 patients of per rectal bleeding was carried out in the department of pathology over 2 years (June 2015 to May 2017). Results: Total 40 lesions of lower gastrointestinal tract were studied. Commonest age group involved was 41-60 years with male preponderance. Neoplastic lesions accounted for majority amongst which predominant lesions were malignant that is adenocarcinoma. Moderately differentiated adenocarcinoma involving rectum were preponderant. Majority of adenocarcinomas were in stage C1 of Astler-Coller staging. Haemorrhoids were the most common nonneoplastic lesion. Conclusion: Malignant lesion is the commonest cause of per rectal bleeding amongst lower gastrointestinal tract lesions.

Authors and Affiliations

Shivani H. Ingale

Keywords

Related Articles

Vancomycin induced Generalized Tonic Clonic Seizure- A Rare Case Report

Vancomycin induced seizure is very rarely documented. Only one case report on vancomycin-induced hypertension with transient blindness and generalized seizure was reported in year 1992. Here we report a case of vancomyci...

Macrophage Distinct Process: Efferocytosis in Oral Cancer

Macrophages and neutrophils are the first defendants to invading pathogens and play a part in host defense against intracellular pathogens. Macrophages come into sight to play a major role in efferocytosis, phagocytosis...

Is Aperture Fixation Superior to Cortical Fixation for Quadruple Hamstring Graft in Anterior Cruciate Ligament Reconstruction

Introduction: ACL is a commonly injured ligament of the knee. The incidence is rising due to increased motor vehicle accident. To regain full activity, its proper reconstruction is essential. Different technique develope...

Cholesterol Lowering Effect Of Philippine Ashitaba (Gynura Procumbens) Crude Aqueous Leaf Extract In Hypercholesterolemic Mice

Gynura procumbens, a medicinal plant with various nutritive benefits, is being utilized as a source of total-cholesterol lowering herb in folk medicine. The Japanese variety of ashitaba has proven scientific basis in low...

A comparison of survival in elderly as compare to young patients in locally advanced esophageal carcinoma treated by definitive chemoradiation.

Introduction: The benefit of definitive chemoradiotherapy (CRT) in elderly patients with locally advanced esophageal cancer is not well established .We perform a single institutional retrospective study of CRT in terms o...

Download PDF file
  • EP ID EP501869
  • DOI -
  • Views 90
  • Downloads 0

How To Cite

Shivani H. Ingale (2018). Clinicopathological Study of Lower Gastrointestinal Tract Lesions in Per Rectal Bleeding Cases. International Journal of Medical Science and Innovative Research (IJMSIR), 3(3), 188-193. https://europub.co.uk/articles/-A-501869