Clinicopathological study of ocular surface squamous neoplasia in non-HIV patients and effect of topical cyclosporine
Journal Title: IP International Journal of Ocular Oncology and Oculoplasty - Year 2017, Vol 3, Issue 1
Abstract
Introduction: Ocular Surface Squamous Neoplasia is a spectrum of conjunctival and corneal epithelial neoplasia manifesting as dysplasia, carcinoma-in-situ and squamous cell carcinoma. Study was aimed to know the clinicopathological manifestations of OSSN in non-HIV patients and efficacy of topical cyclosporine. Methods: 4 patients with conjunctival growth on medial side of eye suspecting OSSN were studied and all 4 underwent wide surgical excision followed by histopathological investigation. Followed up with topical 0.05% cyclosporine drops twice a day for 8 weeks. Results: Case 1 and 2 showed moderately differentiated Squamous cell carcinoma. Case 3 showed full thickness dysplasia and case 4 showed conjunctival tissues with no evidence of malignancy. Case1 showed recurrence after 2 months and case 2 and 3 did not show recurrence. Conclusion: OSSN in Non-HIV patients can present in similar fashion to HIV patients but with better prognosis.
Authors and Affiliations
Dadapeer K, Sahana R. Manipur, Kavitha CV, Pavana Acharya, Lakshmi BR
Keywords
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- EP ID EP292172
- DOI 10.18231/2455-8478 .2017.0014
- Views 94
- Downloads 0
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