Clinicopathological study of Ovarian tumours
Journal Title: Perspectives In Medical Research - Year 2016, Vol 4, Issue 3
Abstract
Introduction: The ovary consists of sex cells, which are totipotential and of mesenchymal cells which are multipotential.So when it becomes neoplastic almost any type of tumour can result. The ovarian tumours manifest as a wide spectrum of clinical, morphological and histological features. Ovarian tumours can occur in women of all ages, but there are differences in the histological types during various decades of life. During infancy and childhood the predominant type is germ cell tumours, where as in adults the epithelial tumours are the most common type. The incidence rate increases with age, peaks at 5th decade. Aims and Objectives: To study the incidence, clinical features, age and parity distribution and complications of ovarian tumours and to evaluate clinicopathological features of ovarian malignancy. Materials and Methods :The present study is a prospective study done on 74 patients of all age groups presenting with ovarian tumours to the Department. of Obstetrics and Gynaecology for the period of 2 years. A detailed clinical history was taken with structured questionnaires. General, systemic and pelvic examinations were done. Complete haemogram, blood sugar level, HIV, HbSAg, urine examination, Pap smear, ultrasonography was done routinely. ECG and chest X ray were done for fitness for anaesthesia or when indicated.Tumour marker CA 125 level estimation was done in clinically suspected cases of malignancy. CT was done in suspected inoperable malignant tumours. Results:The total number of ovarian tumours was 74 and the number of gynaecological admissions was 1251 giving an incidence of 5.91%. Of these 43 were benign, 8 were borderline and 23 were malignant giving a percentage of 58.1%, 10.8% and 31.08% respectively. Conclusion:Ovarian tumours have varying modes of presentation. Benign ovarian tumours present at an early age (3rd decade ) compared to malignant tumours which present in 5th decade. Majority of the patients have symptoms not necessarily gynecological in nature. Malignant ovarian tumours are still diagnosed at a very late stage. Ovarian cancer still a silent killer. A good history, detailed physical examination and investigations like USG, do help to come to an accurate diagnosis, but final diagnosis depends on histopathology.
Authors and Affiliations
Rashmi K S
Hemichorea-Hemiballismus syndrome in Ketotic hyperglycemia
Introduction: Diabetes mellitus is a common disorder in Asian people occasionally presenting with unusual manifestations such as hemichorea-hemiballismus (HC-HB) is a rare manifestation of primary diabetes mellitus. Sinc...
Mammographic breast density patterns and role of supplemental screening by ultrasound
Objectives: To study breast density patterns on mammography�? in local population, to analyse the need for supplemental screening by high resolution ultrasound of both breasts, to compare obtained density patterns with o...
A study of the cardio-depressant actions of harman alkaloids isolated from the seeds of Peganum harmala
Introduction: The plant Peganum harmala is a shrub native to the arid parts of the world including India. It's therapeutic value is attributed to the presence of alkaloids harmala and harmine in the dried ripe seeds. In...
Role of ultrasound guided fine needle aspiration cytology in the diagnosis of abdominal-pelvic lumps
Background: Aspiration cytology is the study of cells, obtained by a fine needle puncture of the mass.The basic principles of fine needle aspiration can be applied to almost any site in the body.Masses arising in the abd...
Comparison of intravaginal misoprostol alone and in combination with intracervical Foley’s catheter for termination of second trimester pregnancy- 3 years study at a tertiary care hospital
Introduction: Termination of pregnancy in second trimester is one of the greatest challenges in modern obstetrics practice and is more risky than during first trimester. Now the main concern of the obstetrician is to pro...