Clonazepam-induced acute liver injury: A case report

Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2017, Vol 7, Issue 12

Abstract

Clonazepam belongs to the benzodiazepine class of drugs (benzodiazepine derivative). It is used both as an anticonvulsant and in the treatment of panic disorder with or without agoraphobia. The most frequent adverse drug reactions of clonazepam are sedation or drowsiness, ataxia or hypotonia, and behavioral disturbances. Hepatomegaly and transient elevations in serum aminotransferases and alkaline phosphatase concentrations may occur in patients receiving this drug, but the frequency of the reaction has not been well defined. Here, we report that an acute psychosis case was the patient’s laboratory reports showed a transient elevation in serum transaminases and alkaline phosphatase levels after clonazepam was administered.

Authors and Affiliations

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M

Keywords

Related Articles

Night shift working and its impact on sleep quality, calorie intake, and serum thyroid stimulating hormone level among health-care workers in a tertiary hospital, Bengaluru

Background: There are several health and social problems which are associated with shift work. This is mainly due to negative working environment and impairment of biological rhythms during the shift work. Aims and Objec...

Effect of single and double strap backpack load carriage on vital capacity in school going children

Background: There has been growing concern among healthcare professionals, parents, and educators that backpack is damaging the back. Load carriage systems supported by the trunk have been shown to decrease certain indic...

Revisiting feedback practises in formative assessment of Indian Medical Schools

The research in formative assessment (FA) has evolved over the years by shifting paradigms from its actual need in medical education to its important components (recent focus). The primary purpose is to make it more bene...

 Variation in pulmonary function tests parameters in different phases of menstrual cycle in healthy female medical students

 Background: Menstrual cycle is a physiological process that occurs in women. It is characterized by periodic vaginal bleeding owing to the shedding of uterine mucosa, which has its own effect on various systems an...

Sleep duration and its association with obesity and overweight in medical students: A cross-sectional study

Background: The prevalence of sleep deprivation is rising globally as is that of obesity. The association between the two is also gaining much evidence. The medical students may be specifically affected due to decreased...

Download PDF file
  • EP ID EP292796
  • DOI 10.5455/njppp.2017.7.0723308072017
  • Views 81
  • Downloads 0

How To Cite

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M (2017). Clonazepam-induced acute liver injury: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 7(12), 1439-1440. https://europub.co.uk/articles/-A-292796