Clonazepam-induced acute liver injury: A case report
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2017, Vol 7, Issue 12
Abstract
Clonazepam belongs to the benzodiazepine class of drugs (benzodiazepine derivative). It is used both as an anticonvulsant and in the treatment of panic disorder with or without agoraphobia. The most frequent adverse drug reactions of clonazepam are sedation or drowsiness, ataxia or hypotonia, and behavioral disturbances. Hepatomegaly and transient elevations in serum aminotransferases and alkaline phosphatase concentrations may occur in patients receiving this drug, but the frequency of the reaction has not been well defined. Here, we report that an acute psychosis case was the patient’s laboratory reports showed a transient elevation in serum transaminases and alkaline phosphatase levels after clonazepam was administered.
Authors and Affiliations
Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M
Keywords
Related Articles
- EP ID EP292796
- DOI 10.5455/njppp.2017.7.0723308072017
- Views 69
- Downloads 0
Hepatoprotective activity of aqueous and ethanolic Bixa orellana L. leaf extracts against carbon tetrachloride-induced hepatotoxicity
Background: There is an increasing incidence of liver failure and lack of effective drugs for liver diseases. Aim and Objective: This study identified the phytochemicals present in aqueous and ethanolic Bixa orellana L....
Clinical profile of chronic daily headache in patient attending tertiary centre
Background: The frequent headache syndrome is among the most challenging disorder that conforms clinician on a routine basis. A major problem with the relatively new form chronic daily headache (CDH) has been its confusi...
The muscular effect of Cobra energy drink on toad (Bufo marinus = Rhinella marina) gastrocnemius fatigue time and contraction force
Background: Cobra energy drink is one of the most popular beverages in the Philippines used by many for its energy-boosting effects. It is known to contain ingredients such as caffeine, B-vitamins, taurine, and ginseng,...
Effects of overnight sleep deprivation on autonomic function and perceived stress in young health professionals and their reversal through yogic relaxation (Shavasana)
Background: Extensive research has been done to demystify the effects of sleep deprivation on cognitive functions, memory, and reasoning ability. However, there is a lacuna in regard to the effects on autonomic function...
Study of psychological predictors and sleep quality in different grades of premenstrual syndrome
Background: Premenstrual syndrome (PMS) is a recurrent, cluster of symptoms and signs that develop during the 10 days before the onset of menses and subside with the onset of menstruation. It is known to affect the women...