Clozapine: the past, present, and future
Journal Title: Open Journal of Psychiatry & Allied Sciences - Year 2015, Vol 6, Issue 2
Abstract
Today even after fifty years of its manufacture the decision to use clozapine still represents a challenge to the clinician because of the complexities involved in accurately assessing its risks and benefits. Debate and uncertainty as to what represents an adequate trial, indications, and the mechanism of action of clozapine is continuing. The author conducted a review of studies that highlighted its historical aspect, the mechanism of action, efficacy, tolerability, and indications of clozapine in current perspective.
Authors and Affiliations
Sekh Afrar Alam, Aparajeeta Baruah, Bondana Timungpi
Keywords
Related Articles
- EP ID EP190203
- DOI 10.5958/2394-2061.2015.00001.4
- Views 142
- Downloads 0
Serum magnesium level and severity of delirium in alcohol withdrawal state
Objectives: Chronic alcohol consumption is associated with nutritional deficiency including micronutrients such as magnesium. Alcohol dependent patients often develop delirium during withdrawal. The relationship between...
Psychosomatic interface: psychological distress and perceived stress in psoriasis patients in a tertiary care hospital in South India
Introduction: Psoriasis is worldwide but the prevalence varies among different ethnicities. Reported prevalence of psoriasis in North India of 0.8% in the seventies has now risen to 2.8%. Psoriasis is associated with sig...
A study to assess the quality of life of undergraduate medical students
Background and aims: Although the quality of life (QoL) of medical students is a relatively well-researched topic in the West, there is a dearth of it in developing countries like India. The aim of this study was to exam...
Prescribing pattern of antipsychotic drugs in the outpatient department of psychiatry in Silchar Medical College and Hospital, Assam
Objective: To study the prescribing pattern of antipsychotic drugs in the outpatient department of psychiatry in Silchar Medical College and Hospital (SMCH) of Assam. Methods: It is a prospective cross-sectional study w...
Psychosocial implications of type 1 diabetes mellitus among children in India: an emerging challenge for social work profession
One of the widespread childhood chronic illnesses, which is seldom talked about is type 1 diabetes mellitus (T1DM). The discussion on T1DM is often missed because the emphasis is majorly on the adult DM or type 2 DM whic...