Clustering of Breast Cancer Cases among Women from Kurdistan Province, Iran: A Population-based Cross-sectional Study
Journal Title: Middle East Journal of Cancer - Year 2018, Vol 9, Issue 1
Abstract
Background: Spatial analysis is one of the required tools of epidemiology and public health sciences. This study intends to detect significant clusters of breast cancer cases in Kurdistan Province, Iran. Methods: We obtained data that pertained to breast cancer cases during 2005-2014 from the Health Deputy at Kurdistan University of Medical Sciences. After application of spatial scan statistics to detect the purely spatial (aggregation of cases in particular locations of space) and space-time (diseases clusters in space that depend on the time period) clusters, we calculated the population attribution risk (%) values to better distinguish the detected clusters. Results: We observed that the second secondary purely spatial cluster (P=0.0051) had the highest population attribution risk (%) of 3.8 and the primary space-time unadjusted cluster (P=0.0019) had the lowest population attribution risk (%) of 0.67 of all the detected clusters. Before we applied the adjustment, both the space-time and purely spatial clusters had similar locations. However, after adjustment for age, the space-time clusters location shifted and population attribution risk (%) values changed (between 0.02 and 0.4). Conclusion: Population attribution risk (%) value differences and clusters’ temporal and spatial variations before and after adjustments can represent disease interventions impact. Additional studies should be conducted to strengthen the registering and reporting system to determine other influencing factors.
Authors and Affiliations
Seyed Mehdi Hosseini, Masoud Parvin, Payam Shokri, Milad Fadaie, Bahman Ghaytasi, Manoochehr Khondabi, Meysam Olfatifar, Ebrahim Chavoshi
Keywords
Related Articles
- EP ID EP302576
- DOI -
- Views 123
- Downloads 0
Congenital Giant Melanocytic Nevus with Malignant Melanoma of the Pleura: Do Primary Pleural Melanomas Exist?
Cases of primary pleural and bronchial melanoma have been described in the literature in the absence of melanocytic cells in the pleura and bronchi. We described a case of congenital giant melanocytic nevus that had a pr...
Small Cell Carcinoma of the Ovary: Report of a Case with Unusual and Aggressive Presentation
Small cell carcinoma of the ovary is an aggressive malignant tumor with no standard treatment. Despite surgery, chemotherapy and radiation, this tumor has a poor prognosis with rapid progression. The authors report a cas...
Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Background: Geographic differences in the incidence of cancers may suggest unique genetic or environmental exposures that impact the risk of acquiring cancer. This research aims to determine the incidence rate and geogra...
Relationship between MMP-11 Expression in Invasive Ductal Breast Carcinoma with its Clinicopathologic Parameters
Background: Breast cancer is one of the most common cancers in the world, particularly in Iran. There are many genomic and molecular factors that cause the occurrence of breast cancer. Many markers are associated with tu...
Simultaneous Integrated Boost by Volumetric Modulated Arc Therapy (VMAT) with Concurrent Mitomycin and Capecitabine in Anal Canal Carcinoma
Background: Combined treatment with radiotherapy and chemotherapy is the standard approach in non-metastatic anal carcinoma. Intensity-modulated radiotherapy and volumetric modulated arc therapy are currently the most ac...