Coinfection of Hepatitis B and C virus among HIV Patients Visiting Specialist Hospital in Ikole Ekiti, Nigeria
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 11
Abstract
Infections from HIV, Hepatitis B and Hepatitis C viruses constitute a major public health challenge in subSaharan Africa, and concurrent morbidities from liver diseases among HIV patients have also been observed due to co-infection with hepatitis B (HBV) and C (HCV) viruses. Free testing of HBV and HCV are not provided alongside free HIV treatment in Nigeria. The aim of this study was to determine the prevalence of HBV and HCV infections among HIV-infected individuals, and describe the socio-demographic features and correlates of HIV and HBV/HCV co-infected patients at Ikole Ekiti, Nigeria. This was a cross- sectional study among HIV individuals attending Specialist Hospital, Ikole Ekiti, Nigeria. One hundred and fifty eight (158) HIV infected individuals were first screened and later tested for marker of HBV and HCV using Enzyme-linked Immunosorbent Assay (ELISA) and their demography information were collected. Data were analysed using packages within SPSS software and a p <0.05 was regarded as significant. Prevalence rates of Hepatitis B and C virus infections obtained were 5.7% and 1.9%, respectively. Two (1.3%) had triple infection of HIV/HBV/HCV. The CD4 count of the sample tested ranged from 2 to 2140cell/mm3 with a mean value of 210cell/mm3 . About 62.5% of them had CD4 T cell count less than 200 cells/mm3. The mean ALT and AST are 23.8 IU/L and 25.9 IU/L respectively. In conclusion, Co-infection with hepatitis B and C virus is common among HIV-infected individuals and this confirm the necessity for routine screening for this markers before initiation of highly active antiretroviral therapy. Also, HBV negative individuals should be immunized with HBV vaccine to improve the prognosis of their HIV status.
Authors and Affiliations
Adeolu Sunday Oluremi
Keywords
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