COLISTIN RESISTANCE GRAM NEGATIVE BACTERIA FROM TRACHEAL ASPIRATES AMONG PATIENTS ADMITTED IN INTENSIVE CARE UNIT OF A TERTIARY CARE HOSPITAL, BANGLADESH
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2019, Vol 6, Issue 6
Abstract
Background: Multidrug-resistant (MDR) Gram negative bacteria (GNB) poses a serious therapeutic problem as no development of newer antimicrobials. In most cases, colistin remains the last viable effective option which leads to an increase exposure of patients to colistin resulting the growing threat of colistin resistance. Objective: The aim of this study was to observe antibiotic susceptibility pattern and prevalence of colistin resistance among gram negative bacteria from tracheal aspirates among patients admitted in ICU of a tertiary care hospital. Materials and Methods: A total of 160 specimens of tracheal aspirates collected from ICU patients were cultured on appropriate media in the department of microbiology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh. Then standard biochemical tests were done to identify the isolated organism. Antibiotic susceptibility profile of isolated bacteria was studied to detect their resistant pattern against colistin. Results: Acinetobacter spp. was the predominant organism (40.59%) found in tracheal aspirate. Among the isolated gram negative bacteris 10.7% were found resistant to colistin. Conclusion: The distribution of colistin resistance pattern in the study is quite unnerving. Producing a local antibiogram database will improve the knowledge of antimicrobial resistance pattern in ICU and will also help to improve treatment strategies.
Authors and Affiliations
Dr. Abu Naser Ibne Sattar
Keywords
Related Articles
- EP ID EP670959
- DOI -
- Views 142
- Downloads 0
“QUALITY PREPRATORY WORK: THE BASIC NEED OF ANALYSIS”.
Quality is compliance to best known standards, processes and specifications. Although analysis of sample is frequently carried out by using sophisticated instruments, the importance of basic laboratory skills cannot be o...
ASSESSEMENT OF SOME CYTOKINES IN PREGNANCY LOSS
Background: Human pregnancy is mediated by complex immunological alterations. Objective: Assessment of some cytokines in pregnancy loss in Abia State, South East, Nigeria. Materials and Methods: This was a cross-sectiona...
THE EFFECTS OF AFRICAN WALNUT (Tetracarpidium conophorum) CRUDE ETHANOLIC ON THE CARDIOVASCULAR SYSTEM, HEMATOLOGICAL PROFILE AND OXIDATIVE STATUS OF MECURY CHLORIDE TREATED WISTAR RATS
Background: Tetracarpidium conophorum commonly referred to as, African walnut has been reported to possess antibacterial activity, anticancer, antidiabetic activities and also boost fertility in male. The influence and m...
EVALUATION OF UTERINE MALFORMATIONS OF PATIENTS ATTENDING MADONNA UNIVERSITY TEACHING HOSPITAL USING ULTRASOUND
Ultrasound is a common diagnostic tool used for the assessment of uterine morphology over several decades.This research is to determine the various uterine abnormalities observed in patients who underwent ultrascan in Ma...
RUDRAKSHA- THE DIVINE BEAD
Rudraksha, a sanctified seed, is famous for its innate electromagnetic properties. According to Hindu mythology this seed stimulates our body energy wheel, giving better harmonization to body-mind and better capability t...