Colonoscopy-assisted Fecal Microbiota Transplant for Outpatient Treatment of Recurrent or Refractory Clostridium Difficile Colitis; Long Term Follow-up of 58 Patients
Journal Title: Journal of Clinical Gastroenterology and Treatment - Year 2016, Vol 2, Issue 1
Abstract
Clostridium difficile infection (CDI) costs the national healthcare system billions of dollars annually, and is reaching epidemic proportions. The current study seeks to evaluate the efficacy and long term outcomes of outpatient colonoscopy-assisted fecal microbiota transplant (FMT) therapy in between 2011-2013 for recurrent or refractory CDI as part of a single center experience. Among 58 patients who underwent FMT and completed the telephone survey, 91.4% were disease free at the 3 month interval, 86.2% at the 6 and 12 month intervals, and 80.5% at the 18 month interval post FMT. Purpose: The current study seeks to evaluate the efficacy and long term outcomes of outpatient colonoscopy-assisted fecal microbiota transplant (FMT) therapy in between 2011-2013 for recurrent or refractory CDI as part of a single center experience.
Coexistence of Acute Appendicitis and Perforated Meckel's Diverticulitis: A Rare Presentation in Older Adults
An appendectomy is one of the most commonly performed abdominal surgical procedures. During this operation, a Meckel's diverticulum (MD) can occasionally be found as an incidental finding, but the coexistence of both app...
Current Status of Colorectal Cancer: From Prevention to Treatment
The management process of colorectal cancer (CRC) comprises a large number of strategic moments for disease treatment. Key points of progress on this disease research range from the the initial screening phase, where scr...
LRAT Promoter Hypermethylation as a Prognostic Marker for Colorectal Cancer Impairs Retinol Metabolism
Retinoids and its derivatives are known to regulate tumor progression. Our previous study in Colorectal Cancer (CRC) has shown that the expression of LRAT, a gene converts excess retinol into retinyl ester to balance ret...
Deception in Crohn's Disease: A Case of Cryptogenic Multifocal Ulcerous Stenosing Enteritis
Cryptogenic multifocal ulcerous stenosing enteritis is a rare idiopathic condition, characterized by multiple small intestinal fibrous strictures with superficial ulcerations. It typically has a chronic or relapsing clin...
Hepatotoxicity from Alpha-Methyldopa During Pregnancy: Two Case Reports
Abstract: A 29-year-old woman in her third pregnancy (at 22 weeks), with a history of arterial hypertension under treatment with enalapril, which medication was switched to α-methyldopa on gestation week 8. She then bega...