Colour Doppler Study in Differentiating Malignancy and Benign Breast Lumps

Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 8

Abstract

Background: Colour Doppler sonography and Pulsed Doppler sonography have been used for last several years to evaluate breast tumours. But there are as yet no reliable investigational standards in colour Doppler sonography to classify the lesion as benign or malignant. Another reasonable goal of breast USG suggested is to identify a sub group of masses that have a very low risk of malignancy so that the option of follow-up can be offered as a viable alternative to biopsy. Accurate differentiation between benign and malignant breast nodules could result in improved care and reduction of patient discomfort, morbidity and health care cost. Aim of this study are to determine whether Doppler and Color flow imaging is reliable in differentiating benign from malignant breast nodules and compare and correlate the ultrasound findings with biopsy results. Materials and Methods: This is an observational study with diagnostic test evaluation. The study population consisted of 64 women over the age of 30 years, presented with a breast nodule either on clinical examination or with mammography. Doppler sonography was performed on arterial vessels within the lesion. Multiple Doppler samples was taken from all the parts of the tumour, including the margins. Only the highest systolic peak flow velocity was used for statistical analysis. Doppler frequency spectra was analysed for peak systolic velocity (Vmax.), resistance index and pulsatility index. Stastistical analysis was done with SPSS v20 software. Biopsy taken from all lesions and results were compared with Doppler results. Results: Blood flow parameters RI, PI and peak systolic velocity showed significant difference between benign and malignant. The cutoff values for these parameters were determined by plotting ROC curves. In our study RI and PI showed higher values compared to benign tumors, due to increased impedance in these lesion. Conclusion: We arrived at cut-off value for RI and PI by drawing ROC curves. RI >0.61 and PI > 0.98 is significant for malignancy.

Authors and Affiliations

Dr Sajitha

Keywords

Related Articles

Evaluation of Glasgow Multifactor Prognostic Scoring System in Acute Pancreatitis - A Study of 25 Cases

Objective: Evaluation of Glasgow Multifactor Prognostic Scoring System in Acute Pancreatitis. Setting & Duration: This study was carried out in Govt. Medical College, Amritsar from November 2013 to May 2015. Methodology:...

A ‘cut off’ value of ‘AP measurement to Transverse measurement Ratio (A/T Ratio)’ for a provisional diagnosis of malignancy in sonologically confirmed solitary nodules of the thyroid

Introduction: The low accuracy of ultrasound features for diagnosing malignancyin the thyroid justifies the widespread use of FNAC on sonologically selected nodules. The sonographic feature, ‘height more than width’or in...

Clinical Profile of Thyroid Associated Ophthalmopathy and Relationship of Exophthalmos to Serum T3,T4 Status

Introduction: The ocular symptoms may be the first manifestation in an endocrine disorder of thyroid. The ocular manifestations are frequent in hyperthyroid Graves disease but rarely associated with Hashimotos disease, t...

Cardiac Auscultation Versus Two-dimensional Trans thoracic Echocardiography in Native Aortic and Mitral Valve diseases in Erbil City

Background: Echocardiography is use for diagnosis and assessment of valvular heart disease as there are many valve diseases that are silent on clinical auscultation. Objective: To identify the sensitivity of auscultation...

Download PDF file
  • EP ID EP529964
  • DOI -
  • Views 94
  • Downloads 0

How To Cite

Dr Sajitha (2017). Colour Doppler Study in Differentiating Malignancy and Benign Breast Lumps. Journal of Medical Science And clinical Research, 5(8), 27241-27249. https://europub.co.uk/articles/-A-529964