Combination of targeted multikinase inhibitor and radioiodine: a new strategy of treatment for advanced differentiated thyroid carcinoma

Journal Title: Journal of Surgery : Concepts & Practice - Year 2023, Vol 28, Issue 6

Abstract

Advanced differentiated thyroid carcinoma (ADTC) lacks effective treatment options, and has a poor prognosis, which is an urgent clinical problem to be resolved. Targeted multikinase inhibitor(MKI) has been approved for the treatment of radioiodine refractory differentiated thyroid carcinoma, and have recently been recommended as a preoperative neoadjuvant therapy agents for locally ADTC. Although radioiodine therapy is the standard postoperative treatment for ADTC, it has certain limitations. MKI combined with radioiodine therapy is expected to become a new strategy of treatment for ADTC.

Authors and Affiliations

Wei LIU

Keywords

Related Articles

Recent advances in subtyping of biliary tract carcinoma

Biliary tract carcinoma exhibits high heterogeneity at the genomic, epigenetic, and molecular expression levels. The patients even with the same pathological morphology and clinical stage of biliary tract malignant tumor...

Application of pylorus-preserving gastrectomy in surgical treatment for early gastric cancer and interpretation of guidelines and consensus

Endoscopic resection (ER) and laparoscopic surgery are the main methods for treatment of early gastric cancer (EGC). Radical gastrectomy(RG) and lymph node dissection are required for the patients who don’t meet the indi...

The necessity and approach for updating the circulatory system assessment in initial phase post-burn

For resolving the major problems of the optimization of the formula of resuscitation and the basis for circular decision-making in the treatment of anesthesia and sedation-analgesia in inital phase post-burn, we propose...

<![CDATA[Research progress in organ preservation strategies for early rectal cancer]]>

<![CDATA[This review explored recent advancements in organ preservation strategies for early rectal cancer. Although total mesorectal excision (TME) remains the standard treatment, there is a growing interest in organ pr...

Download PDF file
  • EP ID EP750924
  • DOI 10.16139/j.1007-9610.2023.06.06
  • Views 27
  • Downloads 0

How To Cite

Wei LIU (2023). Combination of targeted multikinase inhibitor and radioiodine: a new strategy of treatment for advanced differentiated thyroid carcinoma. Journal of Surgery : Concepts & Practice, 28(6), -. https://europub.co.uk/articles/-A-750924