Combined BIS and Serum Neuron Specific Enolase in the predictive value of cardiopulmonary resuscitation patients.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 10
Abstract
Objective To evaluate the prognostic value of the bispectral index (BIS)and neuron-specific enolase (NSE) in patient with cardiopulmonary resuscitationpatients. Methods Forty-four patients with restoration of spontaneous circulation (ROSC) after CPR were treated with MTH. The BIS values were recorded and the serum NSE was measured at: 24 h, 48 h, and 72 hours respectively after ICU admission. Neurological outcome was classified according to the Pittsburgh cerebral performance category (CPC 1 to 5) at 3 months after ICU discharge. Results Thirteen patients had agood neurological outcome with CPC score 1-3, and thirty-one patients had apoor neurological outcome with CPC 4-5 at 3 months. Compared with good prognosis group, the NSE values were significantly higher in the poor prognosis group on day 2 and day 3 after admission [48 h:( 77.0±11.4) vs. Cpc4-5: (38.2±23.9)ng/mL；72 h:(87.0±9.3) vs. Cpc4-5: (45.8±26.4)ng/mL,P＜0.05. NSE increased in the poor neurological outcome group at 48h and 72h, and decreased significantly in the good group at the same time[△NSE 24 h-48 h：(37.3±28.7)ng/mL vs.(-10.2±12.1)ng/mL；△NSE 48 h-72h：(5.4±13.2) ng/mL vs. (- 4.3±4.2 ng/mL), P<0.05]. Over the 72hof monitoring, the mean BIS values were lower in the poor prognosis group compared to the good prognosis group at 48 h [(39.2±24.1) vs. (78.0±12.4);72 h; (45.7±26.4) vs. (89.0±7.3), P＜0.05. Conclusions The values of BIS and NSE were effective prognostic indicators for the neurological outcome of patients with MTH after CPR.
Authors and Affiliations
Shashank Sharma, Ren Quo Qing, Yin Xiao Juan
Keywords
Related Articles
- EP ID EP402373
- DOI 10.9790/0853-1710081318.
- Views 77
- Downloads 0
A Case Report of Juvenile Male with Inflammatory Bowel Disease with Grade I Hemorrhoids with Enteropathic Arthritis.
Enteropathic arthritis (EA) is a spondyloarthritis (SpA) which occurs in patients with inflammatory bowel diseases (IBDs) and other gastrointestinal diseases. Diagnosis is generally established on the medical history and...
A Comparitive study of Morbidity and Mortality in Enteric perforation between Primary repair and Primary Ileostomy with delayed closure
Perforation peritonitis is one of the most common surgical emergency in India and one of its main cause is Typhoid caused by bacterium Salmonella typhi. The spread of infection is usually by faeco-oral route. In underdev...
Prosthodontic Rehabilitation of Maxillary Anterior Ridge Defect With Fixed - Removable Bridge System: A Case Report
It has been well documented that anterior ridge defects present in a patient are challenging to treat (especially aesthetically).To treat such defects when edentulous anterior portion of maxillary ridge has both inadequa...
A Study of The Bacteriological Profile of Chronic Suppurative Otitis Media In Tertiary Facility of Moinabad Belt (Rangareddy District, Telangana State, India)
Introduction: Chronic suppurative otitis media is one of the most common infectious disease worldwide. Also its known for its recurrence and persistence despite adequate treatment. It is caused by a wide variety of micro...
Failures of Crowns and Bridges in Dental School Patients in Jeddah, Saudi Arabia
Abstract:The complications of fixed partial dentures and single crowns have a great importance to be evaluated. The objectives of this study were to determine the prevalence of complications associated with crowns and br...