Combined effect of plant growth regulators based on pyridine n-oxide derivatives and some pesticides of different chemical groups

Abstract

The aim of this work was to determine the character and type of combined action of plant growth regulators —Ivin and Poteytin with pesticides of different chemical groups. Methods. Toxicological —acute toxicity (LD50), clinical signs, the type of combined action. Results. The study combined effect plant growth regulators — Ivin (2,6-dimethyl pyridine N-oxide) and Poteytin (complex of 2,6-dimethyl pyridine N-oxide with succinic acid) with some pesticides in izotoxic doses corresponding 1 LD50 or 1/2 LD50 (in 1:1) showed that both plant growth regulators reduce acute oral toxicity of pesticides and severity of clinical signs of toxicity in rats. The character of the intoxication in rats under the combined effect was due to the influence of the individual pesticide. For the combined action of most investigated pesticides with Ivin is characteristic antagonism, but for Ivin with lambda-cyhalothrin — potentiation of toxicity. For Poteytin combinations with studied pesticides also preferred antagonism, with exception for Poteytin with lambda-cyhalothrin or flutriafol —potentiation of toxicity and with imidacloprid or cypermethrin —summation of toxicity. Conclusions. Plant growth regulators Ivin and Poteytin in most cases reduce the toxicity of studied pesticides and severity of clinical signs of intoxication. Antagonism was establish for the combined action of Ivin with 2,4-D-2-ethylhexyl, tebukonazole, difenoconazole, flutriafol, cypermethrin, thiamethoxam, chlorpyrifos, imidacloprid and potentiation of toxicity for the combined action Ivin with lambda-cyhalothrin. Also, antagonism was found at the combined action of Poteytin with 2,4-D-2-ethylhexyl, tebukonazole, difenoconazole, thiamethoxam and chlorpyrifos, summation — for Poteytin with imidacloprid and cypermethrin, and potentiation of toxicity — for Poteytin with flutriafol and lambda-cyhalothrin.

Authors and Affiliations

O. P. Vasetska

Keywords

Related Articles

Family of nuclear peroxisome proliferator-activated receptors (PPARS): biological role in metabolic adaptation part III. PPARγ and its role in autophagy, inflammation, carcinogenesis and reproductive system upon the exposure to xenobiotics (report 2)

Objective. Analysis and summary of the current concept of biological and physiological role of nuclear peroxisome pro-liferator-activated receptor gamma (PPARγ) in the development and functioning of reproductive system,...

Методологічні аспекти проблеми забезпечення хімічної безпеки лакофарбових матеріалів в країнах Євросоюзу та України

Цель работы. Провести сравнительный анализ законодательных решений, правовой базы, методологии, стандартов, действующих в странах Евросоюза и Украины, направленных на внедрение управленческих решений в системе экологизац...

Отсутствие модифицирующего эффекта тербутилазина на канцерогенез молочной железы, индуцированный полициклическим углеводородом — 7,12 диметилбензантраценом у крыс

Цель работы — изучить возможность промоторного эффекта Тербутилазина на канцерогенез молочной железы, индуцированный полициклическим углеводородом 7,12 дибензантраценом (ДМБА) у крыс-самок Wistar Han. Материалы и методы....

Токсиколого-гигиеническая характеристика гербицида Астарг 125 EC, КЭ

Цель работы. Изучить токсичность генерика технического хизалофоп-п-этила, токсикологические и гигиенические свойства препарата на его основе — Астарг 125ЕС, КЭ (хизалофоп-п-этил, 125 г/л) и разработать вопросы регламента...

Regulation of the field toxico-biological studies of pesticides through the example of EU countries. Challenge for Ukraine. (Review of regulatory and scientific and methodological documents)

The establishment of a free trade zone within the framework of EU-Ukraine Association Agreement provides the necessary measures to achieve the relevant national standards regarding the level of European and international...

Download PDF file
  • EP ID EP306431
  • DOI -
  • Views 126
  • Downloads 0

How To Cite

O. P. Vasetska (2017). Combined effect of plant growth regulators based on pyridine n-oxide derivatives and some pesticides of different chemical groups. Український журнал сучасних проблем токсикології, 79(3), 26-33. https://europub.co.uk/articles/-A-306431