Comparasion of oral clonidine and oral atenolol as premedication in patients posted for laparoscopic cholecystectomy under general anaesthesia.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 6
Abstract
Aim and Objectives: To assess the effect of oral clonidine and oral atenolol as premedication on hemodynamic stability and side effects if any in patients undergoing laparoscopic cholecystectomy. Material and Methods: The study included total 50 patients of (age 15 – 50 years) ASA grade I and II were randomly divided into two groups of 25 each. Patients received oral clonidine 5mcg/kg in group C and oral atenolol 1mg/kg in group A, 90 minutes prior to induction. Induction and maintainence of general anaesthesia was performed by the same standard protocol for both groups. Various study parameters i.e. hemodynamic effect (PR, SBP, DBP & MAP) and side effects were recorded and statistically analyzed. Results: Better hemodynamic stability was obtained in clonidine group compared to that of atenolol group & there were no serious side effects both in the groups. Conclusion: We conclude that oral clonidine is better than atenolol in terms of hemodynamic stability without any side effects.
Authors and Affiliations
Vijay Patil
Keywords
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