COMPARATIVE COMPOSITIONS AND ANTIBACTERIAL ACTIVITY OF THE ESSENTIAL OILS OF ANTHEMIS NOBILIS L. AND ANTHEMIS MIXTA L. (ASTERACEAE)
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2016, Vol 8, Issue 7
Abstract
Objective: To evaluate the chemical composition of essential oils from aerial parts of Anthemis nobilis (An) and Anthemis mixta L (Am). and investigate their antibacterial property.Methods: The essential oils were isolated by hydro distillation and analyzed by GC and GC-MS. The disc diffusion and Agar dilution methods were used to screen the antibacterial activity against referenced and/or clinically isolated (HS) strains of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella enterica, Klebsiella pneumonia and Shighuelle sonnei.Results: The main constituents of An essential oil were 3-methyl-2-buten-1-yl cyclopropane carboxylate (29.3%), vinyl-2,2-dimethylbutanoate (24.2%), glycidyl methacrylate (9.9%), 2-methylbutyl-2-mehylbutyrate (9.1%), isobutyl isobutyrate (7.8%) and 3,3,4-trimethylhexane (6.2%), while Am essential oil was mainly characterized by α-thujone (51.8%), β-thujone (14.6%), borneol (7.3%) and 3-hexen-1-ol (4.9%). An and Am essential oils exhibited the best antibacterial activity against the following strains of Escherichia coli ATCC 25922 (25±1.20, 32±1.00 mm), Pseudomonas aeruginosa ATCC 27853 (23±0.87, 32±0.76 mm) and Staphylococcus aureus ATCC 43300 (21±1.44, 25±1.24 mm inhibition zone diameters, respectively). Minimum inhibitory concentration (MICs) values of these oils were ranged from 32-128µg/ml.Conclusion: From this study, it can be concluded that the chemical composition of the essential oils was related to their antibacterial activity.Keywords: Anthemis nobilis L., Anthemis mixta L., Chemical composition, Antibacterial activity
Authors and Affiliations
Wafa Tadrent, Khaldoun Bachari, Zahia Kabouche
Keywords
Related Articles
- EP ID EP576291
- DOI -
- Views 70
- Downloads 0
ANTIOXIDANT, FREE RADICAL SCAVENGING ACTIVITY AND GC-MS STUDIES ON PEDILANTHUS TITHYMALOIDES (L.) POIT
Objective: To evaluate the methanolic extract of the leaves of Pedilanthus tithymaloides for total phenol, total flavonoid, total antioxidant and free radical scavenging ability and detect the phytoconstituents using GC-...
EFFECT OF A BINARY BLEND COMPOSED OF POLOXAMER AND PVP ON AQUEOUS SOLUBILITY OF GRISEOFULVIN
Objective: The aim of this study was to improve the aqueous solubility of a poorly water soluble drug griseofulvin.Methods: To accomplish this goal a technique of solid dispersion with polyvinyl pyrolidone (k30) and polo...
METHOD DEVELOPMENT, VALIDATION AND STABILITY STUDIES FOR THE DETERMINATION OF LURASIDONE HYDROCHLORIDE IN BULK AND TABLET DOSAGE FORM BY RP-HPLC
Objective: To develop a simple, rapid, sensitive, precise, accurate, economical and validated reverse phase high performance liquid chromatographic (RP-HPLC) method for the estimation of lurasidone hydrochloride in table...
COMPUTATIONAL DOCKING AND IN SILICO ANALYSIS OF POTENTIAL EFFLUX PUMP INHIBITOR PUNIGRATANE
Objective: Efflux-mediated resistance is a growing therapeutic complication as it reduces the efficacy of antibiotics. In gram-negative bacteria like E. coli and K. pneumoniae, this can be overcome with the help of efflu...
SENNA PLANT INDUCES DISRUPTION ON THE MITOCHONDRIA OF HYMENOLEPIS DIMINUTA
Objective: The present study aims at observing the effects of three species of Senna plants, viz. Senna alata, S. alexandrina and S. occidentalis on the ultrastructure of the mitochondria of the tapeworm, Hymenolepis dim...